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Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2) 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 2, 页码: 747-751
作者:  Zhan, Yang;  Zhang, Xiao-Wei;  Xiong, Ying;  Li, Bo-Liang;  Nan, Fa-Jun
收藏  |  浏览/下载:41/0  |  提交时间:2019/01/08
Interferon-γ in foam cell formation and progression of atherosclerosis 期刊论文
Clinica Chimica Acta, 2015, 卷号: 441, 页码: 33-43
作者:  Xiao-HuaYu;  JianZhang;  Xi-LongZheng;  Yun-HuaYang;  Chao-KeTang
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/27
IFN-γ  interferon-γ  IFNGR  IFN-γ receptor  VSMC  vascular smooth muscle cell  IL  interleukin  LPS  lipopolysaccharide  TNF-α  tumor necrosis factor-α  STAT  signal transducer and activator of transcription  NF-κB  nuclear factor-κB  TLR  Toll-like receptor  Tyr  tyrosine  Ser  serine  PI3Ks  phosphatidyl inositol-3 kinases  miRNAs  microRNAs  TGF-β  transforming growth factor-β  Blimp-1  B lymphocyte-induced maturation protein-1  Bcl-6  B cell lymphoma-6  NOD2  nucleotide-binding oligomerization domain 2  JAK  Janus kinase  GAS  IFN-γ activation sequences  ERK  extracellular signal-regulated kinase  PKC  protein kinase C  SOCS  suppressor of cytokine signaling  IP-10  inducible protein-10  ox-LDL  oxidized low-density lipoprotein  SRs  scavenger receptors  ACAT1  Acyl coenzyme A:cholesterol acyltransferase 1  ABCA1  ATP-binding cassette transporter A1  apo E  apolipoprotein E  MMP  matrix metalloproteinase  IFN-γ  Foam cells  Atherosclerosis  Myocardial infarction  Stroke  
Interferon-γ in foam cell formation and progression of atherosclerosis 期刊论文
Clinica Chimica Acta, 2015, 卷号: 441, 页码: 33-43
作者:  Yu, Xiao-Hua;  Zhang, Jian;  Zheng, Xi-Long;  Yang, Yun-Hua*;  Tang, Chao-Ke
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/27
IFN-γ  interferon-γ  IFNGR  IFN-γ receptor  VSMC  vascular smooth muscle cell  IL  interleukin  LPS  lipopolysaccharide  TNF-α  tumor necrosis factor-α  STAT  signal transducer and activator of transcription  NF-κB  nuclear factor-κB  TLR  Toll-like receptor  Tyr  tyrosine  Ser  serine  PI3Ks  phosphatidyl inositol-3 kinases  miRNAs  microRNAs  TGF-β  transforming growth factor-β  Blimp-1  B lymphocyte-induced maturation protein-1  Bcl-6  B cell lymphoma-6  NOD2  nucleotide-binding oligomerization domain 2  JAK  Janus kinase  GAS  IFN-γ activation sequences  ERK  extracellular signal-regulated kinase  PKC  protein kinase C  SOCS  suppressor of cytokine signaling  IP-10  inducible protein-10  ox-LDL  oxidized low-density lipoprotein  SRs  scavenger receptors  ACAT1  Acyl coenzyme A:cholesterol acyltransferase 1  ABCA1  ATP-binding cassette transporter A1  apo E  apolipoprotein E  MMP  matrix metalloproteinase  IFN-γ  Foam cells  Atherosclerosis  Myocardial infarction  Stroke  
Apelin and its receptor APJ in cardiovascular diseases 期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2014, 卷号: 428, 页码: 1-8
作者:  Yu, Xiao-Hua*;  Tang, Zhi-Bin;  Liu, Li-Jing;  Qian, Hong;  Tang, Shi-Lin
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/27
ABCA1  ACAT1  APJ  ATP-binding cassette transporter A1  Ang II  Ang-1  Apelin  Atherosclerosis  BMP  BNP  CAD  COX-2  FGF2  GSK  HDAC  HIF-1alpha  Heart failure  Hypertension  ICAM-1  IRS1  JNK  MCP-1  MEF2  MIRI  NO  PAH  PDGF-BB  PGE2  PI3K  PKB  PKC  PPAR response elements  PPREs  TGF-beta  TNF-alpha  VCAM-1  VEGFA  VSMC  acyl coenzyme A:cholesterol acyltransferase-1  angiopoietin-1  angiotensin II  apo E  apolipoprotein E  bone morphogenic protein  brain natriuretic peptide  c-Jun N-terminal kinase  coronary heart disease  cyclooxygenase-2  fibroblast growth factor 2  glycogen synthase kinase  histone deacetylase  hypoxia-inducible factor 1alpha  insulin receptor substrate 1  intercellular adhesion molecule-1  monocyte chemoattractant protein-1  myocardial ischemia-reperfusion injury  myocyte enhancer factor 2  nitric oxide  phosphatidylinositol 3-kinase  platelet-derived growth factor-BB  prostaglandin E2  protein kinase B  protein kinase C  pulmonary arterial hypertension  transforming growth factor-beta  tumor necrosis factor-alpha  vascular cell adhesion molecule-1  vascular endothelial growth factor type A  vascular smooth muscle cell  
MiR-9 reduces human acyl-coenzyme A:cholesterol acyltransferase-1 to decrease THP-1 macrophage-derived foam cell formation 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 11, 页码: 953-962
作者:  Xu, JJ;  Hu, GJ;  Lu, M;  Xiong, Y;  Li, Q
收藏  |  浏览/下载:19/0  |  提交时间:2015/07/22
Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene 期刊论文
CELL RESEARCH, 2013, 卷号: 23, 期号: 8, 页码: 1007-1024
作者:  Hu, GJ;  Chen, J;  Zhao, XN;  Xu, JJ;  Guo, DQ
收藏  |  浏览/下载:31/0  |  提交时间:2015/07/22
Foam cells in atherosclerosis 期刊论文
Clinica Chimica Acta, 2013, 卷号: 424, 页码: 245-252
作者:  Yu, Xiao-Hua;  Fu, Yu-Chang;  Zhang, Da-Wei;  Yin, Kai*;  Tang, Chao-Ke
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/27
ABCA1  ABCG1  ACAT1  AGE  ATP-binding cassette transporter A1  ATP-binding cassette transporter G1  Atherosclerosis  CD36  CE  ERK1/2  FC  Foam cells  HDL  LDLR  LXR  MAPK  PI3K  PKB  PKC  PPAR response elements  PPAR-gamma  PPREs  RCT  RXR  SR-A  SR-BI  TGF-beta  acyl coenzyme A:cholesterol acyltransferase-1  advanced glycation end products  apoA-I  apoE  apolipoprotein A-I  apolipoprotein E  cholesterol ester  extracellular signal-regulated kinases 1 and 2  free cholesterol  high-density lipoprotein  liver X receptor  low-density lipoprotein receptor  mitogen-activated protein kinase  nCEH  neutral cholesteryl ester hydrolase  ox-LDL  oxidized low-density lipoprotein  peroxisome proliferator-activated receptor-gamma  phosphatidylinositol 3-kinase  protein kinase B  protein kinase C  retinoid X receptor  reverse cholesterol transport  scavenger receptor BI  scavenger receptor class A  transforming growth factor-beta  
Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine 期刊论文
JOURNAL OF LIPID RESEARCH, 2012, 卷号: 53, 期号: 10, 页码: 2092-2101
作者:  Xie, C;  Zhou, ZS;  Li, N;  Bian, Y;  Wang, YJ
收藏  |  浏览/下载:23/0  |  提交时间:2015/07/22
Two novel cis-elements involved in hepatocyte nuclear factor 4 alpha regulation of acyl-coenzyme A:cholesterol acyltransferase 2 expression 期刊论文
2012, 卷号: 44, 期号: 2, 页码: 162-171
作者:  Zhang, Zhuqin;  Liu, Jinjing;  Xi, Yang;  Yang, Ruifeng;  Chen, Houzao
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/13
Hydrogen sulfide inhibits macrophage-derived foam cell formation: 期刊论文
Experimental Biology and Medicine, 2011, 卷号: 236, 期号: 2, 页码: 169-176
作者:  Zhao, Zhan-Zhi;  Wang, Zuo;  Li, Guo-Hua;  Wang, Ren;  Tan, Jian-Miao
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/27


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