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Research Progress in Tumor Therapy Targeting Plasminogen Activator Inhibitor-1 期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2019, 卷号: 46, 期号: 7, 页码: 663-672
作者:  Liu Ji-Hao;  Tang Shu-Zhi;  Hu Li-Hong;  Huang Ming-Dong;  Chen Zhuo
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/01
tPA Point Mutation at Autolysis Loop Enhances Resistance to PAI-1 Inhibition and Catalytic Activity 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 页码: 77-86
作者:  Peng, Shuangzhou;  Xue, Guangpu;  Chen, Shanli;  Chen, Zhuo;  Yuan, Cai
收藏  |  浏览/下载:18/0  |  提交时间:2019/11/21
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
NK cells in cerebral ischemia 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: 109, 页码: 547-554
作者:  Chen, Chen;  Ai, Qi-Di;  Chu, Shi-Feng;  Zhang, Zhao;  Chen, Nai-Hong*
收藏  |  浏览/下载:36/0  |  提交时间:2019/12/27
tPA  tissue plasminogen activator  IS  ischemic stroke  BBB  blood-brain barrier  IFN-γ  interferon-γ  pMCAO  permanent middle cerebral artery occlusion  tMCAO  transient middle cerebral artery occlusion  CX3CR1  CX3CL1 receptor  CNS  central nervous system  AchE  acetylcholine esterase  CFSE  arboxyfluorescein diacetate succinimidyl ester  HI  hypoxic ischemia  MCAO IP-10  interferon-inducible protein-10  IL  interleukin  GFAP  glial fibrillary acidic protein  tg  transgenic  WT  wild-type  APC  antigen presenting cell  SAI  stroke-associated infection  STAT3  signal transducer and activator of transcription-3  HPA  hypothalamic-pituitary-adrenal  cSVD  cerebral small vessel disease  SHR  spontaneously hypertensive rat  CSF  cerebrospinal fluid  aSAH  aneurysmal subarachnoid hemorrhage  DCI  delayed cerebral ischemia  MRI  magnetic resonance imaging  CT  computed tomography  EVs  extracellular vesicles  MSC  mesenchymal stem cell  MNCs  bone marrow-derived mononuclear cells  CpG-ODN  cytosine-guanine oligodideoxynucleotide  TLR9  toll-like receptor 9  TNF  tumor necrosis factor  NK cells  Cerebral ischemia  Inflammation  Immunodpression  Infection  
靶向纤溶酶原激活物抑制剂1的肿瘤治疗研究进展 期刊论文
生物化学与生物物理进展, 2019, 卷号: 46, 期号: 7, 页码: 663
作者:  刘吉昊;  唐述志;  胡立宏;  黄明东;  陈卓
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/01
Intravenous tPA (Tissue-Type Plasminogen Activator ) in Patients With Acute Ischemic Stroke Taking Non-Vitamin K Antagonist Oral Anticoagulants Preceding Stroke 期刊论文
2018, 卷号: 49, 期号: 9, 页码: 2237-2240
作者:  Jin, Chen;  Huang, Ryan J.;  Peterson, Eric D.;  Laskowitz, Daniel T.;  Hernandez, Adrian F.
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
Effects of neuroserpin on clinical outcomes and inflammatory markers in Chinese patients with acute ischemic stroke 期刊论文
NEUROLOGICAL RESEARCH, 2017, 卷号: 39, 期号: 10
作者:  Wu, Weiwen;  Asakawa, Tetsuya;  Yang, Qianghong;  Zhao, Jun;  Lu, Lixia
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Recombinant human TNK tissue-type plasminogen activator (rhTNK-tPA) versus alteplase (rt-PA) as fibrinolytic therapy for acute ST-segment elevation myocardial infarction (China TNK STEMI): protocol for a randomised, controlled, non-inferiority tr 期刊论文
2017, 卷号: 7, 期号: 9, 页码: e016838
作者:  Wang Hai-Bo;  Ji Ping;  Zhao Xing-Shan;  Xu Haiyan;  Yan Xiao-Yan
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/04
A specific plasminogen activator inhibitor-1 antagonist derived from inactivated urokinase 期刊论文
Journal of cellular and molecular medicine, 2016, 卷号: 20, 期号: 10, 页码: 1851-1860
作者:  Gong, Lihu;  Proulle, Valerie;  Fang, Chao;  Hong, Zebin;  Lin, Zhonghui
收藏  |  浏览/下载:71/0  |  提交时间:2019/05/09
Tissue plasminogen activator (tPA) attenuates propofol-induced apoptosis in developing hippocampal neurons 期刊论文
SPRINGERPLUS, 2016, 卷号: 5
作者:  Liang, Chao;  Ding, Ming;  Du, Fang;  Cang, Jing;  Xue, Zhanggang
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/06


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