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上海药物研究所 [18]
四川大学 [18]
长春应用化学研究所 [18]
北京大学 [16]
武汉大学 [16]
厦门大学 [14]
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期刊论文 [214]
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Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer
期刊论文
ADVANCED MATERIALS, 2021, 页码: 12
作者:
Zhou, Fengqi
;
Gao, Jing
;
Tang, Yang
;
Zou, Zhifeng
;
Jiao, Shi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
antigen presentation
autophagy inhibition
immune resistance
immunotherapy
prodrug nanovesicles
In vivo multifunctional fluorescence imaging using liposome-coated lanthanide nanoparticles in near-infrared-II/IIa/IIb windows
期刊论文
NANO TODAY, 2021, 卷号: 38, 页码: 11
作者:
Yang, Junying
;
He, Shuqing
;
Hu, Zhenhua
;
Zhang, Zeyu
;
Cao, Caiguang
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/15
NIR-II
IIa
IIb windows
Fluorescence imaging
Brown adipose tissue
Multifunctional nanoprobe
Rare-earth-doped nanoparticle
Excretory capacity
Fluorescence turn-off magnetic COF composite as a novel nanocarrier for drug loading and targeted delivery
期刊论文
MICROPOROUS AND MESOPOROUS MATERIALS, 2021, 卷号: 311
作者:
Zhao, Kai
;
Gong, Peiwei
;
Huang, Jie
;
Huang, Yan
;
Wang, Dandan
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/11/18
COFs
Fluorescence
Surface modification
Core-shell structure
Drug delivery
Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114
作者:
Fan, Xiaohong
;
Deng, Jiedan
;
Shi, Tao
;
Wen, Huaixiu
;
Li, Junfang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/18
Hepatocellular carcinoma
Topo I
Evodiamine
Cancer-associated fibroblasts (CAFs)
A Hepatocellular Carcinoma Targeting Nanostrategy with Hypoxia-Ameliorating and Photothermal Abilities that, Combined with Immunotherapy, Inhibits Metastasis and Recurrence
期刊论文
ACS NANO, 2020, 卷号: 14, 期号: 10, 页码: 12679-12696
作者:
Zhou, Tianjun
;
Liang, Xiaolong
;
Wang, Peifeng
;
Hu, Yueyang
;
Qi, Yafei
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  |  
浏览/下载:66/0
  |  
提交时间:2021/03/02
hepatocellular carcinoma
prussian blue
photothermal therapy
sorafenib
hypoxia
antiprogrammed death-ligand I
immunotherapy
Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 19, 页码: 10972-10983
作者:
Ma, Yuqin
;
Luo, Qichao
;
Fu, Jie
;
Che, Yanxin
;
Guo, Fei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/05/24
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 7, 页码: 3665-3677
作者:
Qiu, Yunguang
;
Huang, Lu
;
Fu, Jie
;
Han, Chenxia
;
Fang, Jing
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  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
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  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Targeted photodynamic therapy with a novel photosensitizer cercosporin encapsulated multifunctional copolymer
期刊论文
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2020, 卷号: 585, 页码: 8
作者:
Ye, Zhou
;
Hua, Dong
;
Rao, Yijian
;
Bai, Shuo
;
Seeberger, Peter H.
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  |  
浏览/下载:24/0
  |  
提交时间:2020/03/24
Cercosporin
Multifunctional copolymer
Targeted photodynamic therapy
Photosensitizer
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