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上海药物研究所 [10]
大连化学物理研究所 [4]
上海中医药大学 [3]
武汉物理与数学研究所 [2]
厦门大学 [1]
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期刊论文 [28]
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An enhanced strategy integrating offline two-dimensional separation with data independent acquisition mode and deconvolution: Characterization of metabolites of Uncaria rhynchophylla in rat plasma as a case
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 8
作者:
Li, Haojv
;
Wei, Wenlong
;
Li, Zhenwei
;
Wang, Mengyuan
;
Wei, Xuemei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
Off-line 2D separation system
Metabolites characterization in vivo
Data independent acquisition
Multi-dimensional deconvolution
Uncaria rhynchophylla
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:
Pan, Lulu
;
Guo, Shuang
;
Chen, Xiaoyan
;
Jiang, Xiangrui
;
Shen, Jingshan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
TPNI71
Metabolism
UPLC/Q-TOF MS
High-resolution mass spectrometry
Metabolite identification
Simultaneous Determination of Bufalin and Its Nine Metabolites in Rat Plasma for Characterization of Metabolic Profiles and Pharmacokinetic Study by LC-MS/MS
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 15
作者:
Wei, Wenlong
;
Yu, Yang
;
Wang, Xia
;
Yang, Linhui
;
Zhang, Hang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
bufalin
metabolite
quantification
pharmacokinetics
Constituents of Mediterranean Spices Counteracting Vascular Smooth Muscle Cell Proliferation: Identification and Characterization of Rosmarinic Acid Methyl Ester as a Novel Inhibitor
期刊论文
MOLECULAR NUTRITION & FOOD RESEARCH, 2018, 卷号: 62, 期号: 7
作者:
Liu, Rongxia
;
Heiss, Elke H.
;
Waltenberger, Birgit
;
Blazevic, Tina
;
Schachner, Daniel
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  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Mediterranean spices
neointima formation
rosmarinic acid
rosmarinic acid methyl ester
vascular smooth muscle cells
Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice
期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 46, 页码: 1-8
作者:
Li, Zhongyu
;
Jiang, Lei
;
Zhu, Yujuan
;
Su, Wentao
;
Xu, Cong
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/06/20
Microfluidics
Drug Testing
Hepatic Metabolism
Nephrotoxicity
Organs-on-a-chip
Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.
期刊论文
CELL RESEARCH, 2018
作者:
Dai, Junbiao
;
Huang, He
;
Luo, Zhouqing
;
Qi, Shankang
;
Huang, Jing
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  |  
浏览/下载:54/0
  |  
提交时间:2019/01/31
A combination of representative compounds, metabolism platform and diagnostic extraction strategy for characterization of metabolites of Shuang-Huang-Lian oral liquid in vivo by ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry
期刊论文
2018, 卷号: 155, 页码: 216
作者:
Zhang, Feng-Xiang[1,2]
;
Xie, Zhi-neng[1,2]
;
Tang, Xi-yang[1,2]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/17
Comprehensive characterization of in vitro and in vivo metabolites of 2 ',3 ',5 '-tri-O-acetyl-N-6-(3-hydroxyphenyl) adenosine and study of the metabolites distribution in rats by combined methods of HPLC-DAD, off-line cryoNMR, and HPLC-QTOFMS
期刊论文
2018, 卷号: 1096, 页码: 187-200
作者:
Jin, Mengxia
;
Guo, Na
;
Li, Tianqi
;
Liu, Xia
;
Sun, Shanshan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
2 '
3 '
5 '-Tri-O-acetyl-N-6-(3-hydroxyphenyl) adenosine
Metabolites identification
Metabolites distribution
HPLC/HPLC-MS/cryoNMR
Off-line coupling system
Characterization of chemical constituents and rats metabolites of an alkaloidal extract of Alstonia scholaris leaves by liquid chromatography coupled with mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1026, 页码: 43-55
作者:
Cao, Jing
;
Shen, Hong-Mei
;
Wang, Qi
;
Qian, Yi
;
Guo, Hong-Cheng
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2016/09/28
Alstonia scholaris
Alkaloids
UHPLC/qTOF-MS
Metabolites identification
Herbal medicine
Characterization of TPN729 metabolites in humans using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 卷号: 117, 页码: 217-226
作者:
Zhu, Yunting
;
Li, Liang
;
Deng, Pan
;
Chen, Xiaoyan
;
Zhong, Dafang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
TPN729
UPLC/Q-TOF MS
Metabolite identification
Metabolic pathways
Human
Sildenafil
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