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Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149
作者:
Pan, Lijia
;
Nie, Litong
;
Yao, Sheng
;
Bi, Aiwei
;
Ye, Yang
收藏
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浏览/下载:26/0
  |  
提交时间:2020/12/24
neuroblastoma
bufalin
chemical proteomics
ETC
mitochondria
Simultaneous determination of cinobufagin and its five metabolites in rat plasma by LC-MS/MS for characterization of metabolic profiles and pharmacokinetic study
期刊论文
ANALYTICAL METHODS, 2019, 卷号: 11, 期号: 42, 页码: 5464-5471
作者:
Wei, Wenlong
;
Li, Haojv
;
Li, Zhenwei
;
Qu, Hua
;
Da, Juan
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  |  
浏览/下载:55/0
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提交时间:2020/07/01
Simultaneous Determination of Bufalin and Its Nine Metabolites in Rat Plasma for Characterization of Metabolic Profiles and Pharmacokinetic Study by LC-MS/MS
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 15
作者:
Wei, Wenlong
;
Yu, Yang
;
Wang, Xia
;
Yang, Linhui
;
Zhang, Hang
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  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
bufalin
metabolite
quantification
pharmacokinetics
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
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  |  
浏览/下载:65/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
Cytochrome p450 3a enzymes are key contributors for hepatic metabolism of bufotalin, a natural constitute in chinese medicine chansu
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 10
作者:
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
;
Zhang, Feng
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  |  
浏览/下载:87/0
  |  
提交时间:2019/05/08
Bufotalin
Cytochrome p450 3a (cyp3a)
Hydroxylation
Human liver microsomes (hlms)
Docking simulations
Pluronic F127-based micelles for tumor-targeted bufalin delivery
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019, 卷号: 559
作者:
Wang, Haijun
;
Williams, Gareth R.
;
Wu, Jianrong
;
Wu, Junzi
;
Niu, Shiwei
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  |  
浏览/下载:20/0
  |  
提交时间:2019/12/04
Thermo-responsive
Redox-responsive
Bufalin
F127-based micelles
Cross-linking
Controlled release
High-intensity focused ultrasound enhances the effect of bufalin by inducing apoptosis in pancreatic cancer cells
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12
作者:
Ning, Zhouyu
;
Zhu, Zhenfeng
;
Wang, Haiyong
;
Zhang, Chenyue
;
Xu, Litao
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  |  
浏览/下载:36/0
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提交时间:2019/12/05
extracorporeal shockwave therapy
bufalin
apoptosis
pancreatic neoplasms
New therapeutic aspects of steroidal cardiac glycosides: the anticancer properties of Huachansu and its main active constituent Bufalin
期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19
作者:
Cheng, Chien-shan
;
Wang, Jiaqiang
;
Chen, Jie
;
Kuo, Kuei Ting
;
Tang, Jian
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Bufalin
Huachansu
Anti-cancer
Traditional Chinese Medicine
In situ phase transition of microemulsions for parenteral injection yielding lyotropic liquid crystalline carriers of the antitumor drug bufalin
期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 卷号: 173
作者:
Garamus, Vasil M.
;
Li, Na
;
Drechsler, Markus
;
Zou, Aihua
;
Gong, Yabin
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  |  
浏览/下载:119/0
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提交时间:2019/12/05
Bufalin
Encapsulation
In situ phase transition
Liquid crystalline carrier
SAXS
Drug release
Bioavailability
Bufalin-Loaded CaP/DPPE-PEG-EGF Nanospheres: Preparation, Cellular Uptake, Distribution, and Anti-Tumor Effects
期刊论文
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2019, 卷号: 15, 期号: 2
作者:
Xu, Jie
;
Sun, Ying
;
Yuan, Zeting
;
Bao, Yijie
;
Li, Rongxin
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  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Colon Cancer
Nanosphere
Bufalin
Tumor Target
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