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科研机构
中国科学院大学 [4]
北京大学 [3]
清华大学 [1]
大连理工大学 [1]
兰州大学 [1]
昆明植物研究所 [1]
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期刊论文 [12]
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2013 [1]
2012 [3]
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2009 [1]
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Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2016, 卷号: 94, 页码: 110-120
作者:
Xu, Jianqiang
;
Cheng, Qing
;
Arner, Elias S. J.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/09
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
作者:
Liu, Jinhua
;
Mu, Chenglong
;
Yue, Wen
;
Li, Jie
;
Ma, Biao
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2013/10/16
Thioredoxin reductase
Bim
ROS
Apoptosis
Cancer
Genome-wide analysis of putative peroxiredoxin in unicellular and filamentous cyanobacteria
期刊论文
BMC EVOLUTIONARY BIOLOGY, 2012, 卷号: 12, 页码: 220
作者:
Cui, Hongli
;
Wang, Yipeng
;
Wang, Yinchu
;
Qin, Song
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2013/03/08
Peroxiredoxin
Structure
Phylogeny and evolution
Comparative genomics
Cyanobacteria
Small molecule inhibitors of mammalian thioredoxin reductase
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2012, 卷号: 52, 期号: 2
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
Thioredoxin
Redox
Cancer
Selenocysteine
Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent
期刊论文
free radical biology and medicine, 2012
Wang, Lihui
;
Yang, Zhiyu
;
Fu, Jianing
;
Yin, Hanwei
;
Xiong, Kun
;
Tan, Qiang
;
Jin, Hongwei
;
Li, Jing
;
Wang, Tianyu
;
Tang, Wanchen
;
Yin, Jin
;
Cai, Gaoxiong
;
Liu, Mi
;
Kehr, Sebastian
;
Becker, Katja
;
Zeng, Huihui
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
Mammalian thioredoxin reductase 1
Thioredoxin
Ethaselen
Enzyme inhibitor
Selenium compound
Anticancer agent
Free radicals
GLUTATHIONE-REDUCTASE
CANCER-THERAPY
MOLECULAR-MECHANISM
GROWTH-INHIBITION
ANTITUMOR QUINOLS
ESCHERICHIA-COLI
CARCINOMA-CELLS
LUNG-CARCINOMA
HUMAN PLACENTA
IN-VITRO
Novel mechanism of ethaselen in poorly differentiated colorectal RKO cell growth inhibition: Simultaneous regulation of TrxR transcription, expression and enzyme activity
期刊论文
differentiation, 2011
Yin, Hanwei
;
Li, Jing
;
Xiong, Kun
;
Wang, Lihui
;
Wang, Tianyu
;
Tan, Qiang
;
Fu, Jianing
;
Ren, Xiaoyuan
;
Zeng, Huihui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/10
Thioredoxin reductase
Ethaselen
RKO cell
LoVo cell
Poorly differentiated
Wnt/beta-catenin
THIOREDOXIN REDUCTASE INHIBITOR
CANCER STEM-CELLS
BETA-CATENIN
PROGENITOR CELLS
TGF-BETA
IN-VITRO
APOPTOSIS
PROTEIN
GENE
LINES
Molecular bases of thioredoxin and thioredoxin reductase-mediated prooxidant actions of (-)-epigallocatechin-3-gallate
期刊论文
Free radical biology and medicine, 2010, 卷号: 49, 期号: 12, 页码: 2010-2018
作者:
Zhang, Huihui
;
Cao, Dong
;
Cui, Wei
;
Ji, Mingjuan
;
Qian, Xiaohong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/05/10
Thioredoxin
Thioredoxin reductase
(-) epigallocatechin 3 gallate
Egcg
Ros
Auto oxidation
Expression and oxidative stress tolerance studies of glutaredoxin from cyanobacterium Synechocystis sp PCC 6803 in Eseherichia coli
期刊论文
2010, 2010
Li, M
;
Huang, W
;
Yang, Q
;
Liu, XG
;
Wu, QY
收藏
  |  
浏览/下载:8/0
Augmented antitumor effects of combination therapy of cisplatin with ethaselen as a novel thioredoxin reductase inhibitor on human A549 cell in vivo
期刊论文
investigational new drugs, 2010
Tan, Qiang
;
Li, Jing
;
Yin, Han-wei
;
Wang, Li-hui
;
Tang, Wan-chen
;
Zhao, Fang
;
Liu, Xin-min
;
Zeng, Hui-hui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
Ethaselen
Thioredoxin reductase inhibitor
Cisplatin
Non-small cell lung cancer
Combination chemotherapy
Synergistic effect
LUNG-CANCER CELLS
MAMMALIAN THIOREDOXIN
POSSIBLE INVOLVEMENT
CYCLE ARREST
APOPTOSIS
CARCINOMA
DESIGN
GROWTH
LINES
CIS-DIAMMINEDICHLOROPLATINUM(II)
Inhibition of mammalian thioredoxin reductase by black tea and its constituents: implications for anticancer actions
期刊论文
Biochimie, 2009, 卷号: 91, 期号: 3, 页码: 434-444
作者:
Du, Yatao
;
Wu, Yunfei
;
Cao, Xueli
;
Cui, Wei
;
Zhang, Huihui
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/05/10
Thioredoxin reductase
Black tea
Theaflavins
Anticancer
Pro-oxidant
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