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CORC

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Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:  Zheng, Wei;  Wang, Zhen;  Jiang, Xiangrui;  Zhao, Qingjie;  Shen, Jingshan
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
Linaclotide in irritable bowel syndrome with constipation: A Phase 3 randomized trial in China and other regions 期刊论文
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2018, 卷号: 33, 期号: 5
作者:  Yang, Yunsheng;  Fang, Jingyuan;  Guo, Xiaozhong;  Dai, Ning;  Shen, Xizhong
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05
Formaldehyde regulates vascular tensions through nitric oxide-cGMP signaling pathway and ion channels 期刊论文
Chemosphere, 2018, 卷号: 193, 页码: 60-73
作者:  Zhang, Quanxi*;  Tian, Peiru;  Zhai, Miaomiao;  Lei, Xiaodong;  Yang, Zhenhua
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/23
Formaldehyde  Thoracic aorta ring  Vascular tension  Ion channels  Signal pathway  4-AP  4-aminopyridine  ACh  acetylcholine  l-NAME  l  NG-nitro-l-arginine methyl ester  l  ACE  angiotensin-converting enzyme  VSMCs  vascular smooth muscle cells  BKCa  big-conductance Ca2+-activated K+ channel  FA  formaldehyde  IbTx  iberiotoxin  iNOS  inducible nitric oxide synthase  KATP  ATP-sensitive K+ channel  eNOS  endothelial nitric oxide synthase  Kv  voltage-dependent K+ channel  sGC  soluble guanylate cyclase  NE  norepinephrine  nNOS  neuronal nitric oxide synthase  NS-2028  4H-8-bromo-1,2,4-oxadiazolo(3,4-d)benz(b)(1,4)oxazin-1-one  PGI2  prostacyclin  PKC  protein kinase C  cGMP  cyclic guanosine monophosphate  TEA  tetraethylammonium  
Chemical synthesis and structural analysis of guanylate cyclase C agonist linaclotide 期刊论文
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29
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收藏  |  浏览/下载：4/0  |  提交时间：2020/10/26
Probing the Molecular Mechanism of Human Soluble Guanylate Cyclase Activation by NO in vitro and in vivo 期刊论文
Scientific Reports, 2017, 卷号: 7
作者:  Pan, Jie/55270660200[0];  Yuan, Hong/56941225100[1];  Zhang, Xiaoxue/57129146600[2];  Zhang, Huijuan/57129160700[3];  Xu, Qiming/55845259300[4]
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/05
Entry of water into the distal heme pocket of soluble guanylate cyclase beta 1 H-NOX domain alters the ligated CO structure: a resonance Raman and in silico simulation study 期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 49, 页码: 43707-43714
作者:  Zhang, Yuebin;  Chen, Lei;  Xu, Haoran;  Li, Yan;  Li, Chen
收藏  |  浏览/下载：15/0  |  提交时间：2019/06/20
Guanylate cyclase-C signaling pathway regulates intestinal inflammatory injury and epithelial barrier function in Caco-2 cells 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2016, 卷号: 9, 期号: 9
作者:  Wang, Yijie;  Lan, Danfeng;  Niu, Junkun;  Miao, Jiarong;  Dong, Xiangqian
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/04
Expression of guanylate cyclase-C, guanylin, and uroguanylin is downregulated proportionally to the ulcerative colitis disease activity index 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Lan, Danfeng;  Niu, Junkun;  Miao, Jiarong;  Dong, Xiangqian;  Wang, Hong
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/04
Use of clinically relevant responder threshold criteria to evaluate the response to treatment in the Phase III PATENT-1 study 期刊论文
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2015, 卷号: 34, 期号: 3
作者:  Langleben, David;  Galie, Nazzareno;  He, Jianguo;  Huang, Yigao;  Humbert, Marc
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/19
Dysfunctional nitric oxide signalling increases risk of myocardial infarction 期刊论文
NATURE, 2013, 卷号: 504, 期号: 7480
作者:  Erdmann, Jeanette;  Stark, Klaus;  Esslinger, Ulrike B.;  Rumpf, Philipp Moritz;  Koesling, Doris
收藏  |  浏览/下载：37/0  |  提交时间：2015/05/19

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