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上海药物研究所 [17]
兰州大学 [13]
四川大学 [11]
西北高原生物研究所 [10]
昆明植物研究所 [7]
清华大学 [1]
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期刊论文 [65]
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浏览/检索结果:
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Antineoplastic activity of isoliquiritigenin, a chalcone compound, in androgen-independent human prostate cancer cells linked to G2/M cell cycle arrest and cell apoptosis
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 卷号: 821
作者:
Zhang, Biyan
;
Lai, Yun
;
Li, Yufeng
;
Shu, Nan
;
Wang, Zheng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Prostate cancer
Isoliquiritigenin
Cell cycle arrest
CDK1
Microarray profiling
Antineoplastic activity of isoliquiritigenin, a chalcone compound, in androgen-independent human prostate cancer cells linked to G2/M cell cycle arrest and cell apoptosis
期刊论文
European journal of pharmacology, 2018, 卷号: 821, 页码: 57-67
作者:
Zhang Biyan[1]
;
Lai Yun[2]
;
Li Yufeng[3]
;
Shu Nan[4]
;
Wang Zheng[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/24
CDK1
Cell cycle arrest
Isoliquiritigenin
Microarray profiling
Prostate cancer
Development of Selective Cyclin-Dependent Kinase 4 Inhibitors for Antineoplastic Therapies
期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2017, 卷号: 17, 期号: 5, 页码: 646-657
作者:
Guan, Haixing
;
Du, Yongli
;
Han, Weiwei
;
Shen, Jingkang
;
Li, Qunyi
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Anti-cancer agents
cell cycle
clinical trials
cyclin-dependent kinases 4
selective inhibitors
structure activity relationship (SAR)
Venenum Bufonis induces rat neuroinflammation by activiating NF-kappa B pathway and attenuation of BDNF
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 卷号: 186, 页码: 103-110
作者:
Bi, Qi-rui
;
Hou, Jin-jun
;
Qi, Peng
;
Ma, Chun-hua
;
Shen, Yao
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Brain-derived neurotrophic factor (BDNF)
Inflammation
Neurotoxicity NF
NF- < kappa > B pathway
Venenum Bufonis
Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 81-90
作者:
Gong, Chao-Jun
;
Gao, An-Hui
;
Zhang, Yang-Ming
;
Su, Ming-Bo
;
Chen, Fei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Bisthiazole
Histone deacetylases
ZBG
Trifluoromethyl ketones
Synthesis of novel spin-labeled podophyllotoxin derivatives as potential antineoplastic agents: Part XXV
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 11, 页码: 4926-4931
作者:
Yang, L
;
Nan, X
;
Li, WQ
;
Wang, MJ
;
Zhao, XB
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/12/29
Podophyllotoxin
Click chemistry
Cytotoxic activity
Spin-labeled
Synthesis of novel spin-labeled derivatives of 5-FU as potential antineoplastic agents
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 7, 页码: 3269-3273
作者:
Yang, L
;
Wang, MJ
;
Zhang, ZJ
;
Morris-Natschke, SL
;
Goto, M
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/12/29
5-Fluorouracil
Spin-labeled
Nitroxide
Cytotoxicity
Design,synthesis and antiproliferative activity of 3-hydroxy-4-quinolone compounds
期刊论文
Journal of China Pharmaceutical University, 2014, 卷号: 45, 期号: 3, 页码: 286-292
作者:
Wang Fenghua
;
Wang Kai
;
Shen Jianhua
;
Chen Kaixian
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
3-hydroxy-4-quinolone
combination
synthesis
antiproliferative activity
structural-activity relationship
Discovery of a potent dual EGFR/HER-2 inhibitor L-2 (selatinib) for the treatment of cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 69
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
EGFR
HER-2
Lapatinib analogs
NCI-N87
SK-OV-3
Selatinib
Synthesis and mechanistic studies of novel spin-labeled combretastatin derivatives as potential antineoplastic agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 5, 页码: 1248-1256
作者:
Liu, YQ
;
Li, XJ
;
Zhao, CY
;
Nan, X
;
Tian, J
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/12/29
Combretastatin
Spin-labeled
Nitroxide
Cytotoxicity
Mechanistic analysis
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