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CORC

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Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang
收藏  |  浏览/下载：70/0  |  提交时间：2021/05/24
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 13
作者:  Wang, Ao;  Wang, Yawan;  Meng, Xin;  Yang, Yushe
收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24
Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer 期刊论文
CANCER LETTERS, 2020, 卷号: 475, 页码: 22-33
作者:  Xiao, Ruoxuan;  Ding, Chunyong;  Zhu, Hongwen;  Liu, Xia;  Gao, Jing
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:  Zhu, Kongkai;  Shao, Jingwei;  Tao, Hongrui;  Yan, Xue;  Luo, Cheng
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388
作者:  Tao, Hongrui;  Yan, Xue;  Zhu, Kongkai;  Zhang, Hua
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 423-439
作者:  Yu, Jianjun;  Liu, Jieyu;  Li, Daqiang;  Xu, Lei;  Hong, Duidui
收藏  |  浏览/下载：0/0  |  提交时间：2020/07/01
Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 161, 页码: 543-558
作者:  Yu, Jianjun;  Xu, Lei;  Hong, Duidui;  Zhang, Xiaotuan;  Liu, Jieyu
收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08
Synthesis of Novel Analogs of Thieno[2,3-d] Pyrimidin-4(3H)-ones as Selective Inhibitors of Cancer Cell Growth 期刊论文
BIOMOLECULES, 2019, 卷号: 9, 期号: 10, 页码: 1-10
作者:  Zhang, S (Zhang, Sheng)[ 1 ];  Liu, FZ (Liu, Feize)[ 2,3 ];  Hou, XL (Hou, Xueling)[ 2 ];  Cao, JG (Cao, Jianguo)[ 1 ];  Dai, XL (Dai, Xiling)[ 1 ]
收藏  |  浏览/下载：30/0  |  提交时间：2020/01/15
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文
CANCER LETTERS, 2019, 页码: 105-114
作者:  Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/14
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:  Tian, Qian-Ting;  Ding, Chun-Yong;  Song, Shan-Shan;  Wang, Ying-Qing;  Zhang, Ao
收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08

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