CORC

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CORC

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Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong
收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
收藏  |  浏览/下载：51/0  |  提交时间：2021/05/24
Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13
作者:  Wang, Yuhong;  Mi, Tian;  Li, Yiming;  Kan, Weijuan;  Xu, Gaoya
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
A novel pectin from Polygala tenuifolia blocks A beta(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 161, 页码: 35-43
作者:  Zeng, Hui;  Li, Piaopiao;  Zhou, Lishuang;  Ding, Kan
收藏  |  浏览/下载：13/0  |  提交时间：2020/12/21
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:  Zhang, Xiao-tuan;  Hu, Xiao-bei;  Wang, Han-lin;  Kan, Wei-juan;  Xu, Lei
收藏  |  浏览/下载：49/0  |  提交时间：2020/12/24
Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 144, 页码: 1004-1012
作者:  Zhou, Yue;  Duan, Yanhong;  Huang, Shichao;  Zhou, Xuan;  Zhou, Lishuang
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 223, 页码: 8
作者:  Zeng, Hui;  Huang, Lulin;  Zhou, Lishuang;  Wang, Peipei;  Chen, Xia
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Design, synthesis and biological evaluation of the thioether-containing lenalidomide analogs with anti-proliferative activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 176, 页码: 419-430
作者:  Xiao, Donghuai;  Wang, Yu-jie;  Hu, Xiao-bei;  Kan, Wei-juan;  Zhang, Qiumeng
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01

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