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浏览/检索结果: 共16条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters 期刊论文 CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256 作者:  Dong, Lei;  Zhang, Min-Yu;  Han, Hai-Hao;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：31/0  |  提交时间：2022/01/18 Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora 期刊论文 PLANTA MEDICA, 2021, 页码: 7 作者:  Lei, Chun;  Li, Ya-Nan;  Li, Jia-Nan;  Zhou, Yu-Bo;  Cui, Ming-Jun 收藏  |  浏览/下载：21/0  |  提交时间：2021/12/16 Trewia nudiflora  Euphorbiaceae  maytansinoids  cytotoxicity  tubulin polymerization   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310 作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei 收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01 fungus  Calcarisporium arbuscula  natural product  gene cluster activation  liver fibrosis   Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii 期刊论文 FITOTERAPIA, 2021, 卷号: 153, 页码: 5 作者:  Zong, Jian-Fa;  Zhang, Meng-Meng;  Zhou, Yu-Bo;  Li, Jia;  Hou, Ai-Jun 收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04 Hypericum forrestii (Chittenden) N Robson  Clusiaceae  Acylphloroglucinol meroterpenoid  Hyperiforins A-C  Protein tyrosine phosphatase 1B   Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文 PLANTA MEDICA, 2021, 页码: 10 作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li 收藏  |  浏览/下载：43/0  |  提交时间：2021/11/04 Leguminosae  Rhynchosia volubilis  CatSper  prenylated isoflavonoids  rhynchones A - E   Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis 期刊论文 CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13 作者:  Liu, Ping;  Cong, Xiaoji;  Liao, Shengjie;  Jia, Xinglong;  Wang, Xiaomin 收藏  |  浏览/下载：79/0  |  提交时间：2021/08/17 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang 收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17 Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14 作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei 收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17 SHP2 degradation  Proteolysis targeting chimera (PROTAC)  Thalidomide-based heterobifunctional molecules  E3 ubiquitin ligase  CRBN   Determination of maytansinoids in Trewia nudiflora using QuEChERS extraction combined with HPLC 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7 作者:  Li, Ya-Nan;  Li, Jia-Nan;  Ouyang, Qin;  Zhou, Yu-Bo;  Lei, Chun 收藏  |  浏览/下载：44/0  |  提交时间：2021/05/24 Trewia nudiflora  QuEChERS method  Maytansinoids  HPLC