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科研机构
山东大学 [31]
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期刊论文 [31]
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2019 [3]
2018 [1]
2016 [3]
2015 [2]
2014 [2]
2013 [5]
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Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 3, 页码: 380-386
作者:
Dong, Junze
;
Zhang, Jingya
;
Li, Zilu
;
Asnake, Solomon
;
Zhang, Daoguang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Androgen receptor
Prostate cancer
Antagonists
Pyrazole derivatives
Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 2
作者:
Cui, Ying-Jie
;
Tang, Long-Qian
;
Zhang, Cheng-Mei
;
Liu, Zhao-Peng
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2019/12/11
privileged structure
pyrazoles
tubulin inhibitors
antitumor
antitumor agents
Discovery of novel pyrazole derivatives as potential anticancer agents in MCL
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 9, 页码: 1060-1064
作者:
Ran, Fansheng
;
Liu, Yang
;
Zhang, Daoguang
;
Liu, Meixia
;
Zhao, Guisen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/11
Mantle cell lymphoma
BTK
Irreversible inhibitors
Anticancer
Pyrazole
derivatives
Discovery of novel 5-methyl-1H-pyrazole derivatives as potential antiprostate cancer agents: Design, synthesis, molecular modeling, and biological evaluation
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 91, 期号: 6, 页码: 1113-1124
作者:
Zhang, Daoguang
;
Asnake, Solomon
;
Zhang, Jingya
;
Olsson, Per-Erik
;
Zhao, Guisen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
androgen receptor
AR antagonist
luciferase reporter gene assay
prostate cancer
pyrazole derivative
Design, synthesis and evaluation of pyrazole derivatives as non-nucleoside hepatitis B virus inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 123, 页码: 202-210
作者:
Jia, Haiyong
;
Bai, Fuxiang
;
Liu, Na
;
Liang, Xiaohong
;
Zhan, Peng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/16
HBV
Bioisosterism
Hybrid pharmacophore-based
Non-nucleoside
SAR
Design, Synthesis, and Antitumor Evaluation of 4-Amino-(1H)-pyrazole Derivatives as JAKs Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 7, 期号: 10, 页码: 950-955
作者:
Liang, Xuewu
;
Zang, Jie
;
Zhu, Mengyuan
;
Gao, Qianwen
;
Wang, Binghe
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/16
JAKs
Inhibitors
4-Amino-(1H)-pyrazole
Anticancer
Synthesis and biological evaluation of 3-(4-fluorophenyl)-1H-pyrazole derivatives as androgen receptor antagonists
期刊论文
Anti-Cancer Drugs, 2016, 卷号: 27, 期号: 4, 页码: 278-285
作者:
Guangzhu.Guo
;
Jianzhen.Liu
;
Guanjie.Wang
;
Daoguang.Zh
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
antagonist
pyrazole derivatives
androgen receptor
prostate cancer
Inhibition Mechanism of Novel Pyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives Against Proliferation of A549 and H322 Cancer Cells
期刊论文
Chinese Medical Sciences Journal, 2015, 卷号: 30, 期号: 4, 页码: 260-265
作者:
Shao J.-H.
;
Feng G.-H.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
apoptosis
human umbilical vein endothelial cell
lung cancer cell
p53
pyrazole
Inhibition Mechanism of Novel Pyrazolo[1,5-a]pyrazin-4(5H)-one Derivatives Against Proliferation of A549 and H322 Cancer Cells
期刊论文
Chinese Medical Sciences Journal, 2015, 期号: 04, 页码: 260-265
作者:
Jin-hui Shao
;
Gui-hua Feng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
pyrazole
apoptosis
lung cancer cell
p53
human umbilical vein endothelial cell
Progress of the synthesis of condensed pyrazole derivatives (from 2010 to mid-2013)
期刊论文
European Journal of Medicinal Chemistry: Chimie Therapeutique, 2014, 页码: 311-340
作者:
Meng Li
;
Bao-Xiang Zhao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
Condensed pyrazole derivatives
Synthesis
Bioactivities
Progress
Review
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