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科研机构
上海药物研究所 [21]
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期刊论文 [21]
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2021 [1]
2020 [2]
2018 [2]
2017 [2]
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Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
Stepwise targeting and responsive lipid-coated nanoparticles for enhanced tumor cell sensitivity and hepatocellular carcinoma therapy
期刊论文
THERANOSTICS, 2020, 卷号: 10, 期号: 8, 页码: 3722-3736
作者:
Li, Ying
;
Miao, Yunqiu
;
Chen, Mingshu
;
Chen, Xi
;
Li, Feifei
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
drug delivery
pH sensitive
charge conversion
tumor targeting
hepatocellular carcinoma
Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NF kappa B signaling pathway
期刊论文
ONCOTARGETS AND THERAPY, 2018, 卷号: 11, 页码: 4413-4429
作者:
Xue, Yanshi
;
Yang, Lin
;
Li, Junzun
;
Yan, Yilin
;
Jiang, Qinghui
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/01/08
Zyflamend
cisplatin
bladder cancer
NF kappa B
acquired resistance
The dual-inhibitory effect of miR-338-5p on the multidrug resistance and cell growth of hepatocellular carcinoma
期刊论文
Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 3
作者:
Zhao, Yang
;
Chen, Jing
;
Wei, Wenxin
;
Qi, Xinming
;
Li, Chunzhu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance
期刊论文
CHEMICAL SCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 8012-8018
作者:
Jiang, Yuejing
;
Cheng, Juan
;
Yang, Chengyu
;
Hu, Yongzhou
;
Li, Jia
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Hao, Yongjia
;
Lyu, Jiankun
;
Qu, Rong
;
Sun, Deheng
;
Zhao, Zhenjiang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents
期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 24, 页码: 20578-20591
作者:
Lin, Chenchu
;
Zeng, Hanlin
;
Lu, Junyan
;
Xie, Zuoquan
;
Sun, Wenyi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
acetylation
camptothecin
SIRT1
superoxide dismutase
oxidative stress
Lactate Dehydrogenase B Is Associated with the Response to Neoadjuvant Chemotherapy in Oral Squamous Cell Carcinoma
期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 5
作者:
Sun, Wenyi
;
Zhang, Xiaomin
;
Ding, Xu
;
Li, Huaiqi
;
Geng, Meiyu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth
期刊论文
CANCER LETTERS, 2015, 卷号: 360, 期号: 2, 页码: 257-268
作者:
Huang, Hejing
;
Liu, Huanan
;
Liu, Changmei
;
Fan, Lixia
;
Zhang, Xinwen
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Selective cancer therapy
Unfolded protein response
2DG
UPR disrupter
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