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科研机构
上海药物研究所 [49]
内容类型
期刊论文 [49]
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2021 [7]
2020 [6]
2019 [7]
2018 [9]
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Nanomedicine Strategies to Circumvent Intratumor Extracellular Matrix Barriers for Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021, 页码: 25
作者:
Xu, Xiaoxuan
;
Wu, Yao
;
Qian, Xindi
;
Wang, Yuqi
;
Wang, Jiaoying
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/12/16
cancer therapy
drug delivery
extracellular matrix
nanomedicine
tumor penetration
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:
Wang, Yu-zhe
;
Yang, De-hua
;
Wang, Ming-wei
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/04
glucagon-like peptide-1 receptor
glucose-dependent insulinotropic peptide receptor
peptide 19
LY3298176
heteromerization
type 2 diabetes
Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 181, 页码: 357-368
作者:
Guo, Ciliang
;
Wang, Yeqing
;
Zhang, Shihai
;
Zhang, Xiuqi
;
Du, Zhenyun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
pinnatifida polysaccharide
Colitis
Gut microbiota
Short chain fatty acids
Oxygen-Delivering Polyfluorocarbon Nanovehicles Improve Tumor Oxygenation and Potentiate Photodynamic-Mediated Antitumor Immunity
期刊论文
ACS NANO, 2021, 卷号: 15, 期号: 3, 页码: 5405-5419
作者:
Wang, Zhiwan
;
Gong, Xiang
;
Li, Jie
;
Wang, Hong
;
Xu, Xiaoxuan
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/05/24
polyfluorocarbon
nanovehicle
oxygen
tumor hypoxia
antitumor immunity
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:
Xiao, Xuanzheng
;
Lai, Mengzhen
;
Song, Zilan
;
Geng, Meiyu
;
Ding, Jian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
KRAS
Covalent inhibitor
Pyridopyrimidinone
Antiproliferative effect
Scaffold hopping
Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer
期刊论文
ADVANCED SCIENCE, 2021, 页码: 12
作者:
Sun, Fang
;
Zhu, Qiurong
;
Li, Tianliang
;
Saeed, Madiha
;
Xu, Zhiai
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
glucose metabolism
immunogenic cell death
pancreatic cancer
photoimmunotherapy
prodrug nanoparticles
A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115
作者:
Bian, Youcheng
;
Zeng, Hui
;
Tao, Hong
;
Huang, Lulin
;
Du, Zhenyun
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/24
Polygala tenuifolia
Pectin
Pancreatic cancer
Apoptosis
Autophagy
Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway
期刊论文
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 8, 页码: 6961-6970
作者:
Tao, Hong
;
Chen, Xia
;
Du, Zhenyun
;
Ding, Kan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Wei, Yan
;
Song, Sha
;
Duan, Nianxiu
;
Wang, Feng
;
Wang, Yuxi
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/12/24
membrane type 1-matrix metalloproteinase-activated cilengitide
pancreatic cancer
smart liposomes
vascular promotion
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