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科研机构
上海药物研究所 [296]
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期刊论文 [296]
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内容类型:期刊论文
专题:上海药物研究所
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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma
期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:
Chen, Zi-qi
;
Cao, Zhe-rui
;
Wang, Yi
;
Zhang, Xi
;
Xu, Lan
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/12/16
CYH33
MYC
P300
BET
B cell lymphoma
PI3K
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Applications of Asymmetric Petasis Reaction in the Synthesis of Chiral Amines
期刊论文
ACTA CHIMICA SINICA, 2021, 卷号: 79, 期号: 11, 页码: 1345-1359
作者:
Li, Yi
;
Xu, Ming-Hua
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/01/04
Petasis reaction
chiral amine
boronic acid
asymmetric synthesis
asymmetric catalysis
Dezocine as a potent analgesic: overview of its pharmacological characterization
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Ye, Rong-Rong
;
Jiang, Shuang
;
Xu, Xu
;
Lu, Yan
;
Wang, Yu-Jun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
dezocine
opioid receptors
norepinephrine
serotonin transporter
postoperative pain
anesthesia
NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
期刊论文
CELL REPORTS, 2021, 卷号: 36, 期号: 7, 页码: 20
作者:
Zhou, Zikai
;
He, Guiqin
;
Zhang, Xiaoyun
;
Lv, Xin
;
Zhang, Xiaolin
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/16
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
Identification of novel anti-inflammatory Nur77 modulators by virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:
Ding, Xiaoyu
;
Zhao, Zijie
;
Wu, Yue
;
Zhang, Hao
;
Chen, Kaixian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/08/17
Nur77
Binding site evaluation
Virtual Screening
Inflammation
Histamine activates HinK to promote the virulence of Pseudomonas aeruginosa
期刊论文
SCIENCE BULLETIN, 2021, 卷号: 66, 期号: 11, 页码: 1101-1118
作者:
Wang, Yaya
;
Cao, Qiao
;
Cao, Qin
;
Gan, Jianhua
;
Sun, Ning
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Pseudomonas aeruginosa
Histamine
Metabolism
Host-microbe interaction
Virulence
Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver & ndash;alpha-cell axis
期刊论文
BIOSCIENCE REPORTS, 2021, 卷号: 41, 期号: 6, 页码: 12
作者:
Liu, Qiaofeng
;
Lin, Guangyao
;
Chen, Yan
;
Feng, Wenbo
;
Xu, Yingna
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/16
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
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