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Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan
收藏  |  浏览/下载：56/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：137/0  |  提交时间：2019/06/28
Serum cardiac troponin elevation predicts mortality in patients with pulmonary hypertension: A meta-analysis of eight cohort studies 期刊论文
CLINICAL RESPIRATORY JOURNAL, 2019, 卷号: 13, 期号: 2
作者:  Xu, Shuang-Lan;  Yang, Jiao;  Zhang, Chun-Fang;  Xu, Shuang-Yan;  Zhao, Fang-Yun
收藏  |  浏览/下载：28/0  |  提交时间：2019/12/04
Autophagy in pulmonary hypertension: Emerging roles and therapeutic implications 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 10
作者:  Zhang, Chun-Fang;  Zhao, Fang-Yun;  Xu, Shuang-Lan;  Liu, Jie;  Xing, Xi-Qian
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/04
5-Aza-2 '-deoxycytidine, a DNA methylation inhibitor, attenuates hypoxic pulmonary hypertension via demethylation of the PTEN promoter 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 卷号: 855
作者:  Xing, Xi-Qian;  Li, Bo;  Xu, Shuang-Lan;  Zhang, Chun-Fang;  Liu, Jie
收藏  |  浏览/下载：18/0  |  提交时间：2019/12/04
Chrysin ameliorates ANTU-induced pulmonary edema and pulmonary arterial hypertension via modulation of VEGF and eNOs 期刊论文
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2019, 卷号: 33, 期号: 7
作者:  Lei, Zhang;  Wang, Ye;  Wang, Linlin
收藏  |  浏览/下载：17/0  |  提交时间：2019/12/05
Whole-exome sequencing reveals a novel mutation of MT-ND5 gene in a mitochondrial cardiomyopathy pedigree: Patients who show biventricular hypertrophy, hyperlactacidemia, pulmonary hypertension, and decreased exercise tolerance 期刊论文
ANATOLIAN JOURNAL OF CARDIOLOGY, 2019, 卷号: 21, 期号: 1
作者:  Zhou, Nianwei;  Tang, Lu;  Jiang, Yingying;  Qin, Shengmei;  Cui, Jie
收藏  |  浏览/下载：81/0  |  提交时间：2019/12/05
2-Methoxyestradiol attenuates chronic-intermittent-hypoxia-induced pulmonary hypertension through regulating microRNA-223 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 5
作者:  Hao, Shengyu;  Jiang, Liyan;  Fu, Cuiping;  Wu, Xu;  Liu, Zilong
收藏  |  浏览/下载：21/0  |  提交时间：2019/12/05
Silencing PDK1 limits hypoxia-induced pulmonary arterial hypertension in mice via the Akt/p70S6K signaling pathway 期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 18, 期号: 1
作者:  Di, Ruomin;  Yang, Zhongzhou;  Xu, Peng;  Xu, Yingjia
收藏  |  浏览/下载：19/0  |  提交时间：2019/12/05

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