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科研机构
上海药物研究所 [3]
生态环境研究中心 [2]
成都生物研究所 [1]
西北高原生物研究所 [1]
武汉物理与数学研究所 [1]
内容类型
期刊论文 [8]
发表日期
2019 [8]
学科主题
Chemistry ... [1]
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The molecular mechanism of the antagonistic activity of hydroxylated polybrominated biphenyl (OH-BB80) toward thyroid receptor beta
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 697, 页码: -
作者:
Zhang, Xiaofang
;
Cui, Shixuan
;
Pan, Liumeng
;
Dong, Wenhua
;
Ma, Mei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Hydroxylated brominated biphenyls
Endocrine disrupting effect
Molecular interactions
Metabolic activation
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
收藏
  |  
浏览/下载:264/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation
Binding and activity of sulfated metabolites of lower-chlorinated polychlorinated biphenyls towards thyroid hormone receptor alpha
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 180, 页码: 686-692
作者:
Ren, Xiao-Min
;
Li, Chuan-Hai
;
Zhang, Jian-Qing
;
Guo, Liang-Hong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/09/10
Lower-chlorinated polychlorinated biphenyls
LC-PCB sulfates
TR
Agonistic activity
TH system disruption effect
Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor
期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 13, 页码: 8162-8169
作者:
Lu, Yan
;
Qin, Shanshan
;
Zhang, Bingjie
;
Dai, Antao
;
Cai, Xiaoqing
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
G-quadruplex and duplex DNA binding studies of novel Ruthenium(II) complexes containing ascididemin ligands
期刊论文
JOURNAL OF INORGANIC BIOCHEMISTRY, 2019, 卷号: 196, 页码: 10
作者:
Wumaier, Maierhaba
;
Shi, Jing-Jing
;
Yao, Tian-Ming
;
Hu, Xiao-Chun
;
Gao, Ru-Ru
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Ruthenium complexes
G-quadruplex
Duplex DNA
Ascididemin
Ligand fishing of anti-neurodegenerative components from Lonicera japonica using magnetic nanoparticles immobilised with monoamine oxidase B
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2019, 卷号: 42, 期号: 6, 页码: 1289-1298
作者:
Wu, Gui-Fang
;
Jiang, Xiao-Lan
;
Gong, Yu-Zhou
;
Hu, Ya-Dong
;
Bai, Xiao-Lin
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/10/27
enzyme inhibitors
Lonicera japonica
magnetic nanoparticles
monoamine oxidase B
neurodegenerative diseases
Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay
期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2019, 卷号: 393, 期号: 6
作者:
Qu, Lala
;
Zhang, Xiuli
;
Wang, Jixia
;
Zhou, Han
;
Hou, Tao
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/11/25
Dynamic mass redistribution assay
Endothelin receptor type A
Endothelin receptor type B
High-throughput screening
Ligand binding
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