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科研机构
北京大学 [3]
中国医学科学院 北京... [3]
山东大学 [2]
广州地球化学研究所 [1]
上海药物研究所 [1]
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期刊论文 [10]
发表日期
2020 [1]
2018 [4]
2013 [3]
2012 [2]
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Detecting Vegetation Change in the Pearl River Delta Region Based on Time Series Segmentation and Residual Trend Analysis (TSS-RESTREND) and MODIS NDVI
期刊论文
REMOTE SENSING, 2020, 卷号: 12, 期号: 24, 页码: 25
作者:
Ruan, Zhu
;
Kuang, Yaoqiu
;
He, Yeyu
;
Zhen, Wei
;
Ding, Song
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/11/19
Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H2S biomedicine
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:
Zhu, Yaoqiu
;
Romero, Elkin L.
;
Ren, Xiaodong
;
Sanda, Angel J.
;
Du, Congkuo
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H2S biomedicine (vol 9, 3952, 2018)
期刊论文
2018, 卷号: 9
作者:
Zhu, Yaoqiu
;
Romero, Elkin L.
;
Ren, Xiaodong
;
Sanca, Angel J.
;
Du, Congkuo
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H2S biomedicine
期刊论文
2018, 卷号: 9, 期号: 1, 页码: 3952
作者:
Zhu, Yaoqiu
;
Romero, Elkin L.
;
Ren, Xiaodong
;
Sanda, Angel J.
;
Du, Congkuo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Author Correction: Clopidogrel as a donor probe and thioenol derivatives as flexible promoieties for enabling H2S biomedicine
期刊论文
2018, 卷号: 9, 期号: 1, 页码: 4278
作者:
Zhu Yaoqiu
;
Romero Elkin L
;
Ren Xiaodong
;
Sanca Angel J
;
Du Congkuo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
In Vitro Biotransformation Studies of 2-Oxo-clopidogrel: Multiple Thiolactone Ring-Opening Pathways Further Attenuate Prodrug Activation
期刊论文
毒物学领域的化学研究, 2013
Zhu, Yaoqiu
;
Zhou, Jiang
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  |  
浏览/下载:2/0
  |  
提交时间:2015/11/13
CLOPIDOGREL BIOACTIVATION
ACTIVE METABOLITE
IDENTIFICATION
TICLOPIDINE
RESISTANCE
PRASUGREL
THIENOPYRIDINE
DISPOSITION
INVOLVEMENT
GLUTATHIONE
Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents
期刊论文
acs medicinal chemistry letters, 2013
Zhu, Yaoqiu
;
Zhou, Jiang
;
Jiao, Bo
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  |  
浏览/下载:5/0
  |  
提交时间:2015/11/11
Clopidogrel resistance
clinical variability
prodrug attrition
piperidine deuteration
targeted metabolic shift
bioactivation potentiation
ADENOSINE DIPHOSPHATE
ACTIVE METABOLITE
BIOACTIVATION
RESISTANCE
IDENTIFICATION
AGGREGATION
INVOLVEMENT
TICLOPIDINE
PREVENTION
MECHANISM
Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents
期刊论文
ACS medicinal chemistry letters, 2013, 卷号: 4, 期号: 3, 页码: 349-352
作者:
Yaoqiu Zhu
;
Jiang Zhou
;
Bo Jiao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
Clopidogrel resistance
clinical variability
prodrug attrition
piperidine deuteration
targeted metabolic shift
bioactivation potentiation
Identification of the Significant Involvement and Mechanistic Role of CYP3A4/5 in Clopidogrel Bioactivation
期刊论文
acs medicinal chemistry letters, 2012
Zhu, Yaoqiu
;
Zhou, Jiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/11
Clopidogrel resistance
prodrug attrition
CYP3A4/5
active metabolite potentiation
piperidine metabolism
ANTIPLATELET TREATMENT
RESPONSE VARIABILITY
PLATELET REACTIVITY
CLINICAL-EFFICACY
CYP2C19 GENOTYPE
CYTOCHROMES P450
HIGHLY POTENT
IN-VITRO
METABOLISM
RISK
Overcoming Clopidogrel Resistance: Discovery of Vicagrel as a Highly Potent and Orally Bioavailable Antiplatelet Agent
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 7, 页码: 3342-3352
作者:
Shan, Jiaqi
;
Zhang, Boyu
;
Zhu, Yaoqiu
;
Jiao, Bo
;
Zheng, Weiyi
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/23
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