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Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文
NATURE, 2021, 页码: 24
作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan
收藏  |  浏览/下载:52/0  |  提交时间:2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载:78/0  |  提交时间:2021/08/17
Reply to: Binding site for MDL-801 on SIRT6 期刊论文
NATURE CHEMICAL BIOLOGY, 2021, 页码: 5
作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin
收藏  |  浏览/下载:64/0  |  提交时间:2021/05/24
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong
收藏  |  浏览/下载:33/0  |  提交时间:2020/12/21
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+
作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya
收藏  |  浏览/下载:56/0  |  提交时间:2020/12/24
Dynamic modifications of biomacromolecules: mechanism and chemical interventions 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1459-1471
作者:  Wang, Chu;  Zou, Peng;  Yang, Caiguang;  Liu, Lei;  Cheng, Liang
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
Nature brings new avenues to the therapy of central nervous system diseases-An overview of possible treatments derived from natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 10, 页码: 1332-1367
作者:  Zhang, Junchi;  He, Yang;  Jiang, Xiangrui;  Jiang, Hualiang;  Shen, Jingshan
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载:39/0  |  提交时间:2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载:137/0  |  提交时间:2019/06/28
Fast Solving Method Based on Linearized Equations of Branch Power Flow for Coordinated Charging of EVs (EVCC) 期刊论文
IEEE Transactions on Vehicular Technology, 2019, 卷号: 68, 期号: 5
作者:  Zhang, Jian;  Cui, Mingjian;  Li, Bing;  Fang, Hualiang;  He, Yigang
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/05


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