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浏览/检索结果: 共11条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Exploring the Binding Mechanism of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators in Clinical Trials by Molecular Dynamics Simulations 期刊论文 2018, 卷号: 9, 页码: 1492-1502 作者:  Fu, Tingting[1,2,3];  Zheng, Guoxun[1,2,3];  Tu, Gao[1,2,3];  Yang, Fengyuan[1,2,3];  Chen, Yuzong[4] 收藏  |  浏览/下载：10/0  |  提交时间：2019/11/28 What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation 期刊论文 2018, 卷号: 9, 页码: 1128-1140 作者:  Xue, Weiwei[1,2,3];  Yang, Fengyuan[1,2,3];  Wang, Panpan[1,2,3];  Zheng, Guoxun[1,2,3];  Chen, Yuzong[4] 收藏  |  浏览/下载：12/0  |  提交时间：2019/11/30 Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder 期刊论文 2018, 卷号: 20, 页码: 6606-6616 作者:  Xue, Weiwei[1,2,3];  Wang, Panpan[1,2,3];  Tu, Gao[1,2,3];  Yang, Fengyuan[1,2,3];  Zheng, Guoxun[1,2,3] 收藏  |  浏览/下载：5/0  |  提交时间：2019/11/30 Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification 期刊论文 2018, 卷号: 9 作者:  Fu, Jianbo[1];  Tang, Jing[1,2,3];  Wang, Yunxia[1];  Cui, Xuejiao[1,2,3];  Yang, Qingxia[1,2,3] 收藏  |  浏览/下载：12/0  |  提交时间：2019/11/30 NOREVA: normalization and evaluation of MS-based metabolomics data 期刊论文 2017, 卷号: 45, 页码: W162-W170 作者:  Li, Bo[1,2];  Tang, Jing[1,2];  Yang, Qingxia[1,2,3];  Li, Shuang[1,2];  Cui, Xuejiao[1,2] 收藏  |  浏览/下载：7/0  |  提交时间：2019/11/28 Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT1A receptor in the treatment of major depressive disorder 期刊论文 2017, 卷号: 19, 页码: 28885-28896 作者:  Zheng, Guoxun[1,2,3];  Xue, Weiwei[1,2];  Yang, Fengyuan[1,2,3];  Zhang, Yang[1,2,3];  Chen, Yuzong[4] 收藏  |  浏览/下载：9/0  |  提交时间：2019/11/28 Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD 期刊论文 2017, 卷号: 1861, 页码: 2766-2777 作者:  Wang, Panpan[1,2,3,4];  Fu, Tingting[1,3,4];  Zhang, Xiaoyu[1,3,4];  Yang, Fengyuan[1,3,4];  Zheng, Guoxun[1,3,4] 收藏  |  浏览/下载：12/0  |  提交时间：2019/11/30 Differentiating Physicochemical Properties between Addictive and Nonaddictive ADHD Drugs Revealed by Molecular Dynamics Simulation Studies 期刊论文 2017, 卷号: 8, 页码: 1416-1428 作者:  Wang, Panpan[1,2,3];  Zhang, Xiaoyu[2,3];  Fu, Tingting[2,3];  Li, Shuang[2,3];  Li, Bo[2,3] 收藏  |  浏览/下载：3/0  |  提交时间：2019/11/30 Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 4100-4109 作者:  Yuan, Zigao[1,2];  Chen, Shaopeng[2];  Sun, Qinsheng[2,3];  Wang, Ning[1,2];  Li, Dan[1,2] 收藏  |  浏览/下载：9/0  |  提交时间：2019/04/24 PARP  HDAC  Multitarget  Drug design  Antitumor   Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 281-292 作者:  Yuan, Zigao[1,2];  Sun, Qinsheng[2,3];  Li, Dan[1,2];  Miao, Shuangshuang[2];  Chen, Shaopeng[2] 收藏  |  浏览/下载：6/0  |  提交时间：2019/04/24 Epigenetic targets  Multi-target  Drug design  Antitumor bioactivity  DNMT  HDAC