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长春光学精密机械与物... [9]
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IMM-H004 reduced okadaic acid-induced neurotoxicity by inhibiting Tau pathology in vitro and in vivo
期刊论文
2019
作者:
Wang Yingying
;
Song Xiuyun
;
Liu Dandan
;
Lou Yu-Xia
;
Luo Piao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Alzheimer’s disease
IMM-H004
Tau protein
neuroprotection
okadaic acid
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
IMM-H004 reduced okadaic acid-induced neurotoxicity by inhibiting Tau pathology in vitro and in vivo.
期刊论文
Neurotoxicology, 2019, 卷号: 75, 页码: 221-232
作者:
Wang, Yingying
;
Song, Xiuyun
;
Liu, Dandan
;
Lou, Yu-Xia
;
Luo, Piao
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
*Alzheimer's disease
*IMM-H004
*Neuroprotection
*Okadaic acid
*Tau protein
DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice
期刊论文
2018, 卷号: 9
作者:
Zheng, Shijie[1,2]
;
Xiao, Lirong[1]
;
Liu, Yu[3]
;
Wang, Yujiao[1,2]
;
Cheng, Lin[4]
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/10
The extended application of The Rat Brain in Stereotaxic Coordinates in rats of various body weight
期刊论文
2018, 卷号: 307, 页码: 60-69
作者:
Yang, Pengfei
;
Wang, Zhenzhen
;
Zhang, Zhao
;
Liu, Dandan
;
Manolios, Emmanuel Nicholas
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Stereotaxic procedures
Craniometry
Rat brain atlas
Hypouricemic and Nephroprotective Effects of an Active Fraction from Polyrhachis Vicina Roger On Potassium Oxonate-Induced Hyperuricemia in Rats
期刊论文
2018, 卷号: 43, 期号: 1, 页码: 220-233
作者:
Su, Qibiao
;
Su, Hua
;
Nong, Zhihuan
;
Li, Dongmei
;
Wang, Laiyou
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
Polyrhachis vicina Roger
Hyperuricemia
Nephroprotective
Xanthine oxidase
Uric acid transporters
Inflammatory response
Oxidative stress
Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice
期刊论文
2017, 卷号: 51, 期号: 1, 页码: 1-13
作者:
Gao, Yan
;
Chu, Shifeng
;
Shao, Qianhang
;
Zhang, Meijin
;
Xia, Congyuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Ginsenoside Rg1
cisplatin
liver injury
oxidative stress
Nrf2
Virtual Screening against Phosphoglycerate Kinase 1 in Quest of Novel Apoptosis Inhibitors
期刊论文
2017, 卷号: 22, 期号: 6
作者:
Xia, Jie
;
Feng, Bo
;
Shao, Qianhang
;
Yuan, Yuhe
;
Wang, Xiang Simon
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
apoptosis
phosphoglycerate kinase 1
terazosin
virtual screening
Parkinson's disease
Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice
期刊论文
FREE RADICAL RESEARCH, 2017, 卷号: 51, 期号: 1, 页码: 1-13
作者:
Gao, Yan
;
Chu, Shifeng
;
Shao, Qianhang
;
Zhang, Meijin
;
Xia, Congyuan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
Ginsenoside Rg1
Nrf2
cisplatin
liver injury
oxidative stress
20C, a bibenzyl compound isolated from Gastrodia elata, protects PC12 cells against rotenone-induced apoptosis via activation of the Nrf2/ARE/HO-1 signaling pathway
期刊论文
2016, 卷号: 37, 期号: 6, 页码: 731-740
作者:
Huang Juyang
;
Yuan Yuhe
;
Yan Jiaqing
;
Wang Yanan
;
Chu Shifeng
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/04
bibenzyl compound
Gastrodia elata
rotenone
apoptosis
oxidative stress
Nrf2
neuroprotection
Parkinson's disease
PC12 cells
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