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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:  Han, Yachun;  Xu, Xiaoxuan;  Tang, Chengyuan;  Gao, Peng;  Chen, Xianghui
收藏  |  浏览/下载:29/0  |  提交时间:2019/12/03
ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ  
Mitochondria: A Novel Therapeutic Target in Diabetic Nephropathy. 期刊论文
Current medicinal chemistry, 2017, 卷号: 24, 期号: 29, 页码: 3185-3202
作者:  Yang, Shikun;  Han, Yachun;  Liu, Jun;  Song, Panai;  Xu, Xiaoxuan
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/03
The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1 期刊论文
Redox Biology, 2017, 卷号: 11, 期号: Volume 11, 页码: 297-311
作者:  Xiao, Li*;  Xu, Xiaoxuan;  Zhang, Fan;  Wang, Ming;  Xu, Yan
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/03
p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 29302
作者:  Xu, Xiaoxuan;  Zhu, Xuejing;  Ma, Mingming;  Han, Yachun;  Hu, Chun
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4 期刊论文
BMC Cell Biology, 2015, 卷号: 16, 期号: 1, 页码: 7
作者:  Xiao, Li;  Peng, Xiang;  Liu, Fuyou*;  Tang, Chengyuan;  Hu, Chun
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/03
MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis 期刊论文
Laboratory Investigation, 2015, 卷号: 95, 期号: 7, 页码: 817-832
作者:  Xiao, Li;  Zhou, Xun;  Liu, Fuyou;  Hu, Chun;  Zhu, Xuejing
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
PKC deltapromotes high glucose induced renal tubular oxidative damage via regulating activation and translocation of p66Shc 期刊论文
Oxidative Medicine and Cellular Longevity, 2014, 卷号: 2014, 页码: 746531
作者:  Song, Panai;  Yang, Shikun;  Xiao, Li;  Xu, Xiaoxuan;  Tang, Chengyuan
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/03
Cordycepin inhibits albumin-induced epithelial-mesenchymal transition of renal tubular epithelial cells by reducing reactive oxygen species production 期刊论文
FREE RADICAL RESEARCH, 2012, 卷号: 46, 期号: 2, 页码: 174-183
作者:  Xiao, Li;  Ge, Yan;  Sun, Lin;  Xu, Xiaoxuan;  Xie, Ping
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/03
Urinary TWEAK Level as a Marker of Lupus Nephritis Activity in 46 Cases 期刊论文
Journal of Biomedicine and Biotechnology, 2012, 卷号: 2012, 页码: 359647
作者:  Xuejing, Zhu;  Jiazhen, Tan;  Jun, Li;  Xiangqing, Xu;  Shuguang, Yuan
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
A Multicenter Application and Evaluation of the Oxford Classification of IgA Nephropathy in Adult Chinese Patients 期刊论文
American Journal of Kidney Diseases, 2012, 卷号: 60, 期号: 5, 页码: 812-820
作者:  Zeng, Cai-Hong;  Le, Weibo;  Ni, Zhaohui;  Zhang, Minfang;  Miao, Lining
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/03


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