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科研机构
上海药物研究所 [17]
内容类型
期刊论文 [16]
会议论文 [1]
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2021 [4]
2019 [2]
2018 [2]
2017 [2]
2016 [3]
2015 [2]
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Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402
作者:
Jiao, Shang
;
Guan, Dongliang
;
Xu, Lili
;
Liu, Bo
;
Shi, Weiwei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/01/18
glycopeptide antibiotics
impurity
analytical method
process optimization and development
Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8
作者:
Shi, Weiwei
;
Chen, Feifei
;
Zou, Xiangman
;
Jiao, Shang
;
Wang, Siqi
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/08/17
Vancomycin analogues
LPS binding peptides
Vancomycin-Peptide Conjugates
Antibacterial activity
A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 6
作者:
Hu, Yu
;
Zou, Xiangman
;
Shi, Weiwei
;
Ma, Chenhui
;
Chen, Feifei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
Vancomycin C-terminus modification
Hydrazide derivatives
Native Chemical Ligation
Antibacterial activity
Total and Semisyntheses of Polymyxin Analogues with 2-Thr or 10-Thr Modifications to Decipher the Structure-Activity Relationship and Improve the Antibacterial Activity
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 5746-5765
作者:
Li, Jian
;
Guan, Dongliang
;
Chen, Feifei
;
Shi, Weiwei
;
Lan, Lefu
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/17
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2020/07/01
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
期刊论文
CELL, 2019, 卷号: 179, 期号: 2, 页码: 561-+
作者:
Gao, Qiang
;
Zhu, Hongwen
;
Dong, Liangqing
;
Shi, Weiwei
;
Chen, Ran
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Activation of AhR with nuclear IKK alpha regulates cancer stem-like properties in the occurrence of radioresistance
期刊论文
CELL DEATH & DISEASE, 2018, 卷号: 9
作者:
Yan, Bin
;
Liu, Shuang
;
Shi, Ying
;
Liu, Na
;
Chen, Ling
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  |  
浏览/下载:108/0
  |  
提交时间:2019/01/08
humanpharmacokineticsofginkgoterpenelactonesandimpactofcarboxylationinbloodontheirplateletactivatingfactorantagonisticactivity
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1935
作者:
Liu Xinwei
;
Yang Junling
;
Niu Wei
;
Jia Weiwei
;
Olaleye Olajide E
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/07/01
FACTOR PAF-ACETHER
ENDOTHELIAL-CELLS
BILOBA EXTRACTS
INHIBITION
METABOLISM
QUERCETIN
PLASMA
RUTIN
PON1
PARAOXONASES
Ginkgo biloba
human pharmacokinetics
renal excretion
terpene lactone
monocarboxylate
platelet-activating factor
Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 1056-1070
作者:
Zhuang, Rangxiao
;
Gao, Lixin
;
Lv, Xiaoqing
;
Xi, Jianjun
;
Sheng, Li
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Proteasome inhibitors
Piperazine or piperidine
Non-covalent
Peptidyl derivatives
Anti-cancer
Triptolide Inhibits the AR Signaling Pathway to Suppress the Proliferation of Enzalutamide Resistant Prostate Cancer Cells
期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 7, 页码: 1914-1927
作者:
Han, Yangyang
;
Huang, Weiwei
;
Liu, Jiakuan
;
Liu, Dandan
;
Cui, Yangyan
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Triptolide
Enzalutamide
Castration-resistant prostate cancer
Androgen receptor
Phosphorylation
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