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浏览/检索结果: 共15条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文 MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+ 作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng 收藏  |  浏览/下载：26/0  |  提交时间：2021/12/01 Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7 作者:  Xiong, Juan;  Zhou, Peng-Jun;  Jiang, Hao-Wen;  Huang, Ting;  He, Yu-Hang 收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04 forrestiacids  lipogenesis inhibitors  natural products  structure elucidation  terpenoids   Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15 作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua 收藏  |  浏览/下载：34/0  |  提交时间：2021/11/04 Neo-clerodane Diterpenoids with Hypoglycemic Effects in Vivo from the Aerial Parts of Salvia hispanica L. 期刊论文 CHEMISTRY & BIODIVERSITY, 2021, 页码: 6 作者:  Fan, Min;  Wang, Ting;  Peng, Li-Yan;  Huang, Jun-Shang;  Wu, Xing-De 收藏  |  浏览/下载：20/0  |  提交时间：2021/11/04 Salvia hispanica  neo-clerodane diterpenoid  salvihispin H  type 2 diabetes mellitus   Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Huang, He-ming;  Fan, Shi-jie;  Zhou, Xiao-ru;  Liu, Yan-jun;  Li, Xiao 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 nonalcoholic steatohepatitis  inflammation  histone deacetylase inhibitor  givinostat  epigenetics   Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice 期刊论文 BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 页码: 10 作者:  Chen, Meng-Ting;  Huang, Jun-Shang;  Gao, Ding-Ding;  Li, Ying-Xia;  Wang, He-Yao 收藏  |  浏览/下载：41/0  |  提交时间：2021/08/17 combined treatment  FABP4 inhibitor  liver steatosis  obese type 2 diabetes  rosiglitazone   Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation 期刊论文 MOLECULAR MEDICINE REPORTS, 2021, 卷号: 23, 期号: 5, 页码: 12 作者:   收藏  |  浏览/下载：45/0  |  提交时间：2021/05/24 liver fibrosis  hepatic stellate cell  histone deacetylase inhibitor  epigenetics  givinostat   Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity 期刊论文 MOLECULAR PSYCHIATRY, 2021, 卷号: 26, 期号: 4, 页码: 1162-1177 作者:  Chen, Zhong-Guo;  Wang, Yu-Jun;  Chen, Ruo-Song;  Geng, Fan;  Gan, Chen-Ling 收藏  |  浏览/下载：17/0  |  提交时间：2021/05/24 (-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 10 作者:  Yan, Bing-Chao;  Zhou, Min;  Li, Jian;  Li, Xiao-Nian;  He, Shi-Jun 收藏  |  浏览/下载：55/0  |  提交时间：2021/05/24 bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：145/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial