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科研机构
上海药物研究所 [19]
内容类型
期刊论文 [19]
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2021 [1]
2020 [5]
2019 [3]
2018 [4]
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2015 [2]
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Ketamine activated glutamatergic neurotransmission by GABAergic disinhibition in the medial prefrontal cortex
期刊论文
NEUROPHARMACOLOGY, 2021, 卷号: 194, 页码: 10
作者:
Zhang, Bing
;
Yang, Xili
;
Ye, Luyu
;
Liu, Rui
;
Ye, Binglu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Highly selective monitoring of in-source fragmentation sapogenin product ions in positive mode enabling group-target ginsenosides profiling and simultaneous identification of seven Panax herbal medicines
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2020, 卷号: 1618, 页码: 11
作者:
Zhang, Chun-xia
;
Wang, Xiao-yan
;
Lin, Zhao-zhou
;
Wang, Hong-da
;
Qian, Yue-xin
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
In-source fragmentation
Ginsenoside
Selective ion monitoring
Characteristic chromatogram
Panax
Traditional Chinese medicine formula
Smart Tumor Microenvironment-Responsive Nanotheranostic Agent for Effective Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 11
作者:
Guo, Shi-yan
;
Sun, Di
;
Ni, Da-long
;
Yu, Miao-rong
;
Qian, Kun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
hypoxia relief
mesoporous calcium silicate
sequential functions
sustained drug release
synergetic effects
Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk-Shell Structure Augment Cancer Chemotherapy
期刊论文
NANO LETTERS, 2020, 卷号: 20, 期号: 2, 页码: 936-946
作者:
Nie, Di
;
Dai, Zhuo
;
Li, Jialin
;
Yang, Yiwei
;
Xi, Ziyue
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
cancer cell membrane coating
yolk-shell structure
tumor penetration
membrane fusion
intracellular trafficking
perinuclear aggregation
Oxytocin Exerts Antidepressant-like effect by potentiating dopaminergic synaptic transmission in the mPFC
期刊论文
NEUROPHARMACOLOGY, 2020, 卷号: 162, 页码: 13
作者:
Li, Qian
;
Zhang, Bing
;
Cao, Hang
;
Liu, Wei
;
Guo, Fei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Oxytocin
mPFC
Dopamine
Antidepressant effect
In-depth profiling, characterization, and comparison of the ginsenosides among three different parts (the root, stem leaf, and flower bud) of Panax quinquefolius L. by ultra-high performance liquid chromatography/quadrupole-Orbitrap mass spectrometry
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 29, 页码: 7817-7829
作者:
Wang, Hongda
;
Zhang, Chunxia
;
Zuo, Tiantian
;
Li, Weiwei
;
Jia, Li
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
Panax quinquefolius
Ginsenoside
Q-Orbitrap
Mass defect filter
Metabolomics
Application of multiple chemical and biological approaches for quality assessment of Carthamus tinctorius L. (safflower) by determining both the primary and secondary metabolites
期刊论文
PHYTOMEDICINE, 2019, 卷号: 58, 页码: 12
作者:
Lu, Jia-Xi
;
Zhanga, Chun-Xia
;
Hu, Ying
;
Zhang, Meng-Han
;
Wang, Ya-Nan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
UHPLC/Q-Orbitrap MS
Quantitative H-1 NMR
Carthamus tinctorius
Primary metabolite
Secondary metabolite
Quality evaluation
Design, Synthesis, and Biological Evaluation of Novel DNA Gyrase-Inhibiting Spiropyrimidinetriones as Potent Antibiotics for Treatment of Infections Caused by Multidrug-Resistant Gram-Positive Bacteria
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 2950-2973
作者:
Shi, Chenghui
;
Zhang, Yinyong
;
Wang, Ting
;
Lu, Wenchao
;
Zhang, Shuhua
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:
Guo, Bin
;
Guo, Shimeng
;
Huang, Jing
;
Li, Jingya
;
Li, Jia
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
GPR40 agonist
2,3-Dihydrobenzo[b][1,4]dioxine
Insulin secretion
Type 2 diabetes mellitus
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