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科研机构
上海药物研究所 [142]
内容类型
期刊论文 [138]
会议论文 [4]
发表日期
2022 [1]
2021 [9]
2020 [8]
2019 [2]
2018 [9]
2017 [10]
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共142条,第1-10条
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Multi-level fingerprinting and cardiomyocyte protection evaluation for comparing polysaccharides from six Panax herbal medicines
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 277, 页码: 10
作者:
Liu, Jie
;
Wang, Hong-da
;
Yang, Fei-fei
;
Chen, Bo-xue
;
Li, Xue
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2022/01/04
Panax
Polysaccharide
Oligosaccharide spectrum
Untargeted metabolomics
Cardiomyocyte protection
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/16
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:
Xiao, Meng-Chao
;
Qian, Hui
;
Huang, Chen-Kai
;
Zheng, Bai-Nan
;
Yan, Fang-Zhi
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/11/04
Imatinib
Autophagy
Hepatocarcinoma
Sorafenib
Synergetic effect
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
From Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer
期刊论文
ADVANCED MATERIALS, 2021, 页码: 37
作者:
Saeed, Madiha
;
Chen, Fangming
;
Ye, Jiayi
;
Shi, Yang
;
Lammers, Twan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/17
clinical translation
nanobiomaterials
nanovaccines
normalization cancer immunotherapy
primary and adaptive resistance
tumor immune microenvironment
Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zan, Gui-ying
;
Sun, Xiang
;
Wang, Yu-jun
;
Liu, Rui
;
Wang, Chen-yao
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
depression
social defeat stress
amygdala
κ
opioid receptor
dynorphin
c-fos
ERK
norBNI
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Nosiheptide analogues as potential antibacterial agents via dehydroalanine region modifications: Semi-synthesis, antimicrobial activity and molecular docking study
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 10
作者:
Fan, Yafei
;
Chen, Hangfei
;
Mu, Ning
;
Wang, Wengui
;
Zhu, Kongkai
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Nosiheptide analogues
Semi-synthesis
Antimicrobial activity
Molecular docking
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:
Xiang, Hao-Yue
;
Wang, Xiang
;
Chen, Yan-Hong
;
Zhang, Xi
;
Tan, Cun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
PI3K
Pyrrolo[2,1-f][1,2,4]triazine
Anti-cancer
Target therapy
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