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CORC

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Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong
收藏  |  浏览/下载：72/0  |  提交时间：2022/01/04
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing
收藏  |  浏览/下载：19/0  |  提交时间：2021/12/01
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:  Xiao, Meng-Chao;  Qian, Hui;  Huang, Chen-Kai;  Zheng, Bai-Nan;  Yan, Fang-Zhi
收藏  |  浏览/下载：49/0  |  提交时间：2021/11/04
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Liu, Lu;  Li, Wei;  Yang, Le;  Guo, Zi-tao;  Xue, Hao
收藏  |  浏览/下载：77/0  |  提交时间：2021/08/17
Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 219, 页码: 12
作者:  Rao, Danni;  Li, Heng;  Ren, Xuelian;  Sun, Yaoliang;  Wen, Cuiyun
收藏  |  浏览/下载：27/0  |  提交时间：2021/08/17
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:  Zhang, Hefeng;  Peng, Xia;  Dai, Yang;  Shao, Jingwei;  Ji, Yinchun
收藏  |  浏览/下载：16/0  |  提交时间：2021/06/11
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu
收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载：45/0  |  提交时间：2021/05/24
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24

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