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科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2019 [1]
2018 [2]
2017 [1]
2015 [1]
2014 [1]
2011 [4]
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Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling
期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 10, 页码: 1417-+
作者:
Jiang, Chenxiao
;
Tang, Yegen
;
Ding, Lulu
;
Tan, Renke
;
Li, Xiaojing
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1
期刊论文
NUCLEIC ACIDS RESEARCH, 2018, 卷号: 46, 期号: 2, 页码: 823-839
作者:
Li, Zengxia
;
Cheng, Zhao
;
Raghothama, Chaerkady
;
Cui, Zhaomeng
;
Liu, Kaiyu
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A
期刊论文
CELL CHEMICAL BIOLOGY, 2017, 卷号: 24, 期号: 5, 页码: 605-+
作者:
McClary, Brandon
;
Zinshteyn, Boris
;
Meyer, Melanie
;
Jouanneau, Morgan
;
Pellegrino, Simone
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation
期刊论文
NUCLEIC ACIDS RESEARCH, 2015, 卷号: 43, 期号: 21, 页码: 10157-10167
作者:
Lu, Junyan
;
Jiang, Chenxiao
;
Li, Xiaojing
;
Jiang, Lizhi
;
Li, Zengxia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73
期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 17, 页码: 7691-7704
作者:
Lam, Frankie
;
Abbas, Abdullahi Y.
;
Shao, Hao
;
Teo, Theodosia
;
Adams, Julian
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
CDK9
shRNA
Mnks
eIF4E
kinase inhibitors
PI3K/Akt/mTOR
Ras/Raf/MAPK
Flavopiridol
CGP57380
apoptosis
transcription
translation
drug development
T33, a novel peroxisome proliferator-activated receptor gamma/alpha agonist, exerts neuroprotective action via its anti-inflammatory activities
期刊论文
ACTA PHARMACOLOGICA SINICA, 2011, 卷号: 32, 期号: 9, 页码: 1100-1108
作者:
Wang, Ying
;
Yang, Yu-she
;
Tang, Xi-can
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
stroke
middle cerebral artery occlusion
oxygen-glucose deprivation
astrocytes
BV-2 cells
inflammation
nuclear factor-kappa B
T33
peroxisome proliferator-activated receptor gamma
Crystal structure of the middle domain of human poly(A)-binding protein-interacting protein 1
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 卷号: 408, 期号: 4, 页码: 680-685
作者:
Lei, Jian
;
Mesters, Jeroen R.
;
von Brunn, Albrecht
;
Hilgenfeld, Rolf
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
PABP
Paip1
HEAT domain
Eukaryotic translation initiation factors
X-ray structure
t33anovelperoxisomeproliferatoractivatedreceptoryagonistexertsneuroprotectiveactionviaitsantiinflammatoryactivities
期刊论文
actapharmacologicasinica, 2011, 卷号: 32, 期号: 9, 页码: 1100
作者:
Wang Ying
;
Yang Yushe
;
Tang Xican
;
Zhang Haiyan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
stroke
middle cerebral artery occlusion
oxygen-glucose deprivation
astrocytes
BV-2 cells
inflammation
nuclear factorkappa B
T33
peroxisome proliferator-activated receptor y
T33, a novel peroxisome proliferator-activated receptor y/α agonist, exerts neuroprotective action via its anti-inflammatory activities
期刊论文
Acta Pharmacologica Sinica, 2011, 卷号: 32, 期号: 9, 页码: 1100
作者:
Wang Ying
;
Yang Yushe
;
Tang Xican
;
Zhang Haiyan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
stroke
middle cerebral artery occlusion
oxygen-glucose deprivation
astrocytes
BV-2 cells
inflammation
nuclear factorkappa B
T33
peroxisome proliferator-activated receptor y
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