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期刊论文 [553]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Comparative chromatin dynamics reveal differential thermal tolerance mechanisms between two congeneric oyster species
期刊论文
AQUACULTURE, 2024, 卷号: 579, 页码: 16
作者:
Wang, Chaogang
;
Jiang, Zhuxiang
;
Du, Mingyang
;
Li, Qingyuan
;
Cong, Rihao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/04/07
Crassostrea gigas
Crassostrea angulata
ATAC-seq
RNA-Seq
Thermal tolerance
Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis
期刊论文
Molecular Cancer, 2022, 卷号: 21
作者:
Hua,Jinghan
;
Wang,Xiaolin
;
Ma,Liying
;
Li,Jingxin
;
Cao,Guozhen
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/22
CircVAPA
SCLC
Progression
miR-377-3p
miR-494-3p
IGF1R
AKT
BMS-536924
Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Yu, Dehua
;
Qi, Simin
;
Guan, Xiaoqing
;
Yu, Wenkai
;
Yu, Xuefei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
STAT3
inhibitor
natural product
gastric cancer
terphenyllin
Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 期号: 5, 页码: 1-15
作者:
Liu, XY (Liu, Xiao Yan) [1] , [2] , [3]
;
Peng, J (Peng, Jun) [1] , [2]
;
He, F (He, Fei) [1]
;
Tursun, X (Tursun, Xirali) [4]
;
Li, SP (Li, Shu Ping) [1]
收藏
  |  
浏览/下载:128/0
  |  
提交时间:2022/06/06
shabyar
retinal pigment epithelium
autophagy
aldose reductase
traditional medicine formula
Decreased mitochondrial DNA copy number in nerve cells and the hippocampus during nicotine exposure is mediated by autophagy
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 卷号: 226
作者:
Wang, Hongjuan
;
Chen, Huan
;
Han, Shulei
;
Fu, Yaning
;
Tian, Yushan
收藏
  |  
浏览/下载:114/0
  |  
提交时间:2021/11/15
nicotine
mtDNA copy number
autophagy
mitochondrial abnormalities
Aurora Kinase A as a Diagnostic and Prognostic Marker of Malignant Mesothelioma
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Guo, Zhenying
;
Shen, Li
;
Li, Ningning
;
Wu, Xiaoxiao
;
Wang, Canming
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/01/25
malignant mesothelioma
bioinformatics
biomarkers
tissue microarray
Aurora kinase A
Rhubarb granule promotes diethylnitrosamine-induced liver tumorigenesis by activating the oxidative branch of pentose phosphate pathway via G6PD in rats
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 281
作者:
Huang, Hongwu
;
Liu, Zhenzhen
;
Qi, Xiaoru
;
Gao, Nailong
;
Chang, Jianguo
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/11/15
Rhubarb
Hepatocarcinogenesis
Diethylnitrosamine
The pentose phosphate pathway
Glucose 6 phosphate dehydrogenase
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