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CORC

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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：61/0  |  提交时间：2022/01/18
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04
Solidification of volatile D-Limonene by cyclodextrin metal-organic framework for pulmonary delivery via dry powder inhalers: In vitro and in vivo evaluation 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 606, 页码: 9
作者:  Zhou, Yong;  Zhang, Meijuan;  Wang, Caifen;  Ren, Xiaohong;  Guo, Tao
收藏  |  浏览/下载：101/0  |  提交时间：2021/11/04
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:  Sun, Dongxue;  Gao, Xiaoxia;  Wang, Qiao;  Krausz, Kristopher W.;  Fang, Zhongze
收藏  |  浏览/下载：47/0  |  提交时间：2021/11/04
Preclinical characterization of LOXO-338, a novel, oral and selective BCL2 inhibitor. 期刊论文
CANCER RESEARCH, 2021, 卷号: 81, 期号: 13, 页码: 1
作者:  Brandhuber, Barbara;  Ku, Karin;  Lallena, Maria J.;  Baquero, Carmen;  Choy, Regina
收藏  |  浏览/下载：9/0  |  提交时间：2021/11/04
Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:  Che, Jinxin;  Wang, Zhilong;  Shen, Zheyuan;  Zhuang, Weihao;  Ying, Huazhou
收藏  |  浏览/下载：60/0  |  提交时间：2021/08/17
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:  Liu, Chenglong;  Zhou, Feilong;  Yan, Ziqin;  Shen, Lian;  Zhang, Xichen
收藏  |  浏览/下载：26/0  |  提交时间：2021/06/11
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Meng, Jian;  Zhang, Hua;  Bao, Jing-jing;  Chen, Zhen-dong;  Liu, Xiao-yun
收藏  |  浏览/下载：69/0  |  提交时间：2021/06/11
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Meng, Jian;  Zhang, Hua;  Bao, Jing-jing;  Chen, Zhen-dong;  Liu, Xiao-yun
收藏  |  浏览/下载：70/0  |  提交时间：2021/06/11
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：35/0  |  提交时间：2021/05/24

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