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Ropivacaine suppresses tumor biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signaling axis
期刊论文
BIOENGINEERED, 2021, 卷号: 12
作者:
Zhang, Runze
;
Lian, Yanhong
;
Xie, Kangjie
;
Cai, Yunfang
;
Pan, Yafei
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/10
Ropivacaine
hepatocellular carcinoma
IGF-1R
IGF1R-PI3K-AKT-mTOR signaling
cell cycle
epithelial-mesenchymal transition
An overview of kinase downregulators and recent advances in discovery approaches
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:
Wang, Beilei
;
Wu, Hong
;
Hu, Chen
;
Wang, Haizhen
;
Liu, Jing
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/25
Transdermal delivery of poly-hyaluronic acid-based spherical nucleic acids for chemogene therapy
期刊论文
NANOSCALE, 2021
作者:
Jiang, Kai
;
Zhao, Di
;
Ye, Rui
;
Liu, Xinlong
;
Gao, Chao
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/02/14
CD71-Specific Aptamer Conjugated with Monomethyl Auristatin E for the Treatment of Uveal Melanoma
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2021
作者:
Zhang, Hui
;
Jin, Cheng
;
Zhang, Lin
;
Peng, Bo
;
Zhang, Yibin
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/02/14
uveal melanoma
CD71
aptamer-drug conjugate
targeted drug delivery
tumor-targeted therapy
Innovative Synthesis of PANI/Cu2O Nanocomposite and Its Antibacterial Properties**
期刊论文
CHEMISTRYSELECT, 2021, 卷号: 6, 期号: 47, 页码: 13636-13641
作者:
Zhang, Mengmeng
;
Han, Sha
;
Niu, Xiaohui
;
Li, Hongxia
;
Zhang, Deyi
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  |  
浏览/下载:13/0
  |  
提交时间:2022/03/01
Antibiotics
Cuprous oxide nanoparticles
Drug resistant
Nanocomposites
Polyaniline
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
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  |  
浏览/下载:38/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China[2019ZX09301157-003]
项目
项目编号: 2019ZX09301157-003, 资助机构: National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China, 2021-
-
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  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
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  |  
浏览/下载:24/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202]
项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
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  |  
浏览/下载:164/0
  |  
提交时间:2021/05/24
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