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CORC

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Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao
收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:  Huang, Huoming;  Li, Xueping;  Xie, Peng;  Li, Xinwei;  Xu, XueJun
收藏  |  浏览/下载：28/0  |  提交时间：2021/08/17
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:  Huang, Huoming;  Li, Xinwei;  Guo, Wei;  Zhu, Chen;  Qian, Yuanyuan
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
尼古丁戒断诱发疼痛敏感性升高的中枢神经机制 期刊论文
生理学报, 2021, 卷号: 73, 期号: 06, 页码: 953-962
作者:  钟嘉慧;  毕研芝;  孔亚卓;  陆智杰;  胡理
收藏  |  浏览/下载：42/0  |  提交时间：2022/01/14
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxypheny1)-N-phenylpiperidine-1-carboxamide as novel potent analgesic 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:  Huang, Huoming;  Wang, Wenli;  Xu, Xuejun;  Zhu, Chen;  Wang, Yujun
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts 期刊论文
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225
作者:  Zhang, Bingjie;  Zhao, Simeng;  Yang, Dehua;  Wu, Yiran;  Xin, Ye
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载：92/0  |  提交时间：2020/07/01
Recent Topics in Research and Development of Opioid Drugs 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 38, 期号: 10, 页码: 2625-2632
作者:  Pan Chenling;  Meng Hao;  Wang Liangliang;  Shen Yuchai;  Zuo Zhili
收藏  |  浏览/下载：25/0  |  提交时间：2018/12/18
The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776
作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance 期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 108, 页码: 364-372
作者:  Wang, ZL;  Li, N;  Wang, P;  Tang, HH;  Han, ZL
收藏  |  浏览/下载：6/0  |  提交时间：2017/01/10

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