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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors
期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:
Xu, Jianghong
;
Hu, Yuanyuan
;
Liu, Xiaoqi
;
Gao, Anhui
;
Gao, Lixin
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/12/01
IDH1-R132H inhibitors
synthesis
biological activity
docking
3-(indol-3-yl)-4-(pyrazolo-[3
4-c]pyridazin-3-yl)-maleimides
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:
Huang, Feng
;
Tian, Tian
;
Wu, Yizhe
;
Che, Jinxin
;
Yang, Haiyan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/06/15
Isocitrate dehydrogenase 2
IDH2
mutant
inhibitors
structure-activity relationship
blood cance
An Integrated Regulatory Network Based on Comprehensive Analysis of mRNA Expression, Gene Methylation and Expression of Long Non-coding RNAs (lncRNAs) in Myelodysplastic Syndromes
期刊论文
FRONTIERS IN ONCOLOGY, 2019, 卷号: 9
作者:
Zhao, Xiaoli
;
Yin, Hua
;
Li, Nianyi
;
Zhu, Yu
;
Shen, Wenyi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
myelodysplastic syndromes
differentially expressed genes
methylated genes
microRNAs
lncRNAs
regulatory network
Lenalidomide acesulfamate: Crystal structure, solid state characterization and dissolution performance
期刊论文
Journal of Molecular Structure, 2019, 卷号: 1175, 页码: 852-857
作者:
Chen, Xin
;
Li, Duanxiu
;
Wang, Jianming
;
Deng, Zongwu
;
Zhang, Hailu
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/11/19
Artificial sweeteners
Intermolecular interactions
Lenalidomide
Myelodysplastic syndromes
Single-crystal and powder
Solid state characterization
Solid-state nuclear magnetic resonance
Solubilization
Disruption of erythroid nuclear opening and histone release in myelodysplastic syndromes
期刊论文
CANCER MEDICINE, 2019, 卷号: 8, 期号: 3, 页码: 1169-1174
作者:
Zhao, Baobing
;
Liu, Hui
;
Mei, Yang
;
Liu, Yijie
;
Han, Xu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
chromatin condensation
enucleation
erythropoiesis
myelodysplastic
syndromes
Monosomal karyotypes apart from complex karyotypes independently predict the outcome of myelodysplastic syndrome patients using a fluorescence in situ hybridization panel and conventional cytogenetics
期刊论文
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2019, 卷号: 41, 期号: 4, 页码: 519-529
作者:
Wang, Na
;
Xu, Hongzhi
;
Li, Qing
;
Liu, Jie
;
Sui, Xiaohui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/11
cytogenetics
fluorescence in situ hybridization
monosomal karyotype
myelodysplastic syndromes
prognosis
SOX7 methylation is an independent prognostic factor in myelodysplastic syndromes
期刊论文
PATHOLOGY RESEARCH AND PRACTICE, 2019, 卷号: 215, 期号: 2, 页码: 322-328
作者:
Xu, Zi-jun[1]
;
Tang, Chun-yan[2]
;
Zhou, Jing-dong[3]
;
Ma, Ji-chun[4]
;
Wen, Xiang-mei[5]
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/24
Myelodysplastic syndrome
SOX7
Methylation
Prognosis
Conditioning Regimen of 5-Day Decitabine Administration for Allogeneic Stem Cell Transplantation in Patients with Myelodysplastic Syndrome and Myeloproliferative Neoplasms
期刊论文
2019
作者:
Cao Yi-Geng
;
He Yi
;
Zhang Su-Dong
;
Liu Zi-Xian
;
Zhai Wei-Hua
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/01/03
Allogeneic hematopoietic stem cell transplantation
Decitabine
Myeloablative conditioning regimen
Myelodysplastic syndromes
Myelodysplastic/myeloproliferative neoplasms
Prognostic impact of red blood cell distribution width in myelodysplastic syndromes
期刊论文
2019, 卷号: 186, 期号: 2, 页码: 352-355
作者:
Shi, Zhongxun
;
Li, Bing
;
Huang, Huijun
;
Qin, Tiejun
;
Xu, Zefeng
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/01/03
red blood cell distribution width
myelodysplastic syndrome
genetic mutation
prognosis
FINAL Results of an Phase, Multicenter, Randomied, Controlled OPEN LEVEL Trial: Decitabine Therapy in Patients with Myelodysplastic Syndromes
期刊论文
BLOOD, 2018, 卷号: 132
作者:
Shao, Zonghong
;
Liu, Hui
;
Jiang, Hao
;
Tong, Hongyan
;
Xiang, Ruixiang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/04
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