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CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer
期刊论文
BRITISH JOURNAL OF CANCER, 2020, 页码: 12
作者:
Wang, Lei
;
Wang, Quanren
;
Xu, Piaopiao
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Safety, Efficacy, and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial
期刊论文
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 期号: 17, 页码: 5212-5220
作者:
Li, Qiao
;
Guan, Xiuwen
;
Chen, Shanshan
;
Yi, Zongbi
;
Lan, Bo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib.
期刊论文
Frontiers in genetics, 2019, 卷号: Vol.10, 页码: 25
作者:
Zhen Xiang
;
Shuzheng Song
;
Zhenggang Zhu
;
Wenhong Sun
;
Jaron E Gifts
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/13
LncRNAs
computational analysis
lapatinib
pan-cancer
targeted therapy
Pyrotinib or Lapatinib Combined With Capecitabine in HER2-Positive Metastatic Breast Cancer With Prior Taxanes, Anthracyclines, and/or Trastuzumab: A Randomized, Phase II Study
期刊论文
2019, 卷号: 37, 期号: 29, 页码: 2610-2619
作者:
Ma Fei
;
Ouyang Quchang
;
Li Wei
;
Jiang Zefei
;
Tong Zhongsheng
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/01/03
Fructus mume Extracts Alleviate Diarrhea in Breast Cancer Patients Receiving the Combination Therapy of Lapatinib and Capecitabine
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Song, Changlong
;
Liu, Yuxia
;
Liu, Zhen
;
Ma, Jinshu
;
Xing, Hua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
A randomized phase II trial of pyrotinib plus capecitabine versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer previously treated with taxanes, anthracyclines and/or trastuzumab
期刊论文
CANCER RESEARCH, 2018, 卷号: 78, 期号: 4
作者:
Xu, Binghe
;
Ma, Fei
;
Ouyang, Quchang
;
Li, Wei
;
Jiang, Zefei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
A randomized phase II trial of pyrotinib plus capecitabine versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer previously treated with taxanes, anthracyclines and/or trastuzumab
会议论文
作者:
Xu, Binghe
;
Ma, Fei
;
Ouyang, Quchang
;
Li, Wei
;
Jiang, Zefei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Rapid symptomatic relief of HER2-positive gastric cancer leptomeningeal carcinomatosis with lapatinib, trastuzumab and capecitabine: a case report
期刊论文
BMC CANCER, 2018, 卷号: 18
作者:
Jiao, Xiao-Dong
;
Ding, Chunming
;
Zang, Yuan-Sheng
;
Yu, Guanzhen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Gastric cancer
Leptomeningeal Carcinomatosis
HER2
Lapatinib
miR-494 inhibits cancer-initiating cell phenotypes and reverses resistance to lapatinib by downregulating FGFR2 in HER2-positive gastric cancer
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 42, 期号: 2, 页码: 998-1007
作者:
Yu, Yanxia
;
Yu, Xuejuan
;
Liu, Hong
;
Song, Qingxun
;
Yang, Yongmei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
gastric cancer
microRNA-494
fibroblast growth factor receptor 2
cancer-initiating cells
human epidermal growth factor receptor
2-positive gastric cancer
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