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An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing
收藏  |  浏览/下载:39/0  |  提交时间:2022/01/25
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun
收藏  |  浏览/下载:32/0  |  提交时间:2021/05/24
Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtA 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 15, 页码: 8442-8457
作者:  Yang, Teng;  Zhang, Tao;  Guan, Xiang-Na;  Dong, Ze;  Lan, Lefu
收藏  |  浏览/下载:19/0  |  提交时间:2020/12/24
Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 13, 页码: 7052-7065
作者:  Huang, Fubao;  Hu, Hangchen;  Wang, Kai;  Peng, Chengyuan;  Xu, Wenwei
收藏  |  浏览/下载:41/0  |  提交时间:2020/12/24
Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors 期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2020, 卷号: 35
作者:  Li, Xia;  Ni, Maowei;  Xu, Xiaoling;  Chen, Wei
收藏  |  浏览/下载:21/0  |  提交时间:2020/11/30
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan
收藏  |  浏览/下载:94/0  |  提交时间:2020/07/01
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:  Liu, Xiaoyun;  Li, Wei;  Zhang, Yifan;  Jian, Yong;  Zhao, Qianyu
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Discovery of novel pyrazole derivatives as potential anticancer agents in MCL 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 9, 页码: 1060-1064
作者:  Ran, Fansheng;  Liu, Yang;  Zhang, Daoguang;  Liu, Meixia;  Zhao, Guisen
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/11
Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:  Niu, Ao;  Wang, Yang;  Yang, Yushe;  Wei, Jianhai;  Ding, Jian
收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01


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