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北京大学 [8]
昆明植物研究所 [4]
中南大学 [4]
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武汉大学 [1]
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期刊论文 [22]
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Molecular diversity of fungal inhibitor cystine knot peptides evolved by domain repeat and fusion
期刊论文
FEMS MICROBIOLOGY LETTERS, 2018, 卷号: 365, 期号: 15, 页码: 1-8
作者:
Jingru Zhao
;
Shouli Yuan
;
Gao B(高斌)
;
Zhu SY(朱顺义)
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/10/14
A sodium channel inhibitor ISTX-I with a novel structure provides a new hint at the evolutionary link between two toxin folds
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Rong, Mingqiang
;
Liu, Jiangxin
;
Zhang, Meilin
;
Wang, Gan
;
Zhao, Gang
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2016/09/28
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
A sodium channel inhibitor ISTX-I with a novel structure provides a new hint at the evolutionary link between two toxin folds
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: X, 页码: e29691
作者:
Rong MQ
;
Liu JX
;
Wang GD
;
Zhang YP
;
Hu KF[*]
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2016/07/18
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*(陶怀)
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Diaminodiacid Bridges to Improve Folding and Tune the Bioactivity of Disulfide-Rich Peptides
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 48, 页码: 14276-14281
作者:
Guo, Ye
;
Sun, De-Meng
;
Wang, Feng-Liang
;
He, Yao
;
Liu, Lei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/10/26
Disulfide-rich Peptide
Peptide Therapeutics
Peptide Synthesis
Protein Engineering
Protein Folding
Cloning and Genomic Characterization of a Natural Insecticidal Peptide LaIT1 with Unique DDH Structural Fold
期刊论文
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2015, 卷号: 29, 期号: 5
作者:
Chen, Jing
;
Xu, Yue
;
San, Mingkui
;
Cao, Zhijian
;
Li, Wenxin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Inhibitor Cystine Knot
Disulfide-Directed -Hairpin
Scorpion
Genomic Organization
Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena
期刊论文
Neuropharmacology, 2014, 卷号: 79, 页码: 657-667
作者:
Deng, Meichun*
;
Luo, Xuan
;
Xiao, Yucheng
;
Sun, Zhenghua
;
Jiang, Liping
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
HWTX-XVI
Tarantula toxin
N-type calcium channels
Dorsal root ganglia
Rat vas deferens
Pain model
Analgesic action
HWTX
Huwentoxin
ICK
inhibitor cystine knot
Cav channel
voltage-gated calcium channel
Nav channel
voltage-gated sodium channel
DRG
dorsal root ganglion
TTX
tetrodotoxin
TTX-R
TTX-resistant
TTX-S
TTX-sensitive
IC50
median inhibitory concentration
Kv channel
voltage-gated potassium channel
HPLC
high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
Novel Inhibitor Cystine Knot Peptides from Momordica charantia
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 10, 页码: e75334
作者:
He, Wen-Jun
;
Chan, Lai Yue
;
Clark, Richard J.
;
Tang, Jun
;
Zeng, Guang-Zhi
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2013/11/12
AMINO-ACID-SEQUENCES
TRYPSIN-INHIBITOR
PLASMODIUM-FALCIPARUM
PROTEINASE-INHIBITORS
CYTOTOXIC CYCLOTIDES
MASS-SPECTROMETRY
FOLDING PATHWAYS
LINN SEEDS
KALATA B1
X-RAY
Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
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