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Harmine mitigates LPS-induced acute kidney injury through inhibition of the TLR4-NF-κB/NLRP3 inflammasome signalling pathway in mice.
期刊论文
European journal of pharmacology, 2019, 卷号: 849, 页码: 160-169
作者:
Niu Xiaofeng
;
Yao Qing
;
Li Weifeng
;
Zang Lulu
;
Li Wenqi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/11/19
NLRP3 inflammasome
Acute kidney injury
TLR4-NF-&kappa
B pathway
Inflammation
Harmine
Subchronic toxicity and concomitant toxicokinetics of long-term oral administration of total alkaloid extracts from seeds of Peganum harmala Linn: A 28-day study in rats
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 238
作者:
Wang, Changhong
;
Wang, Youxu
;
Wang, Hanxue
;
Zhang, Liuhong
;
Zhang, Yunpeng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Subchronic toxicity
Concomitant toxicokinetics
Harmaline
Harmine
Peganum harmala
Mechanism-based pharmacokinetics-pharmacodynamics studies of harmine and harmaline on neurotransmitters regulatory effects in healthy rats: Challenge on monoamine oxidase and acetylcholinesterase inhibition.
期刊论文
Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, 卷号: 62
作者:
Jiang Bo
;
Meng Liyuan
;
Zou Nan
;
Wang Hanxue
;
Li Shuping
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/12/05
Acetylcholinesterase
Alzheimer's disease
Harmaline
Harmine
Monoamine oxidases
Neurotransmitters
Potential Pharmacokinetic Drug-Drug Interaction Between Harmine, a Cholinesterase Inhibitor, and Memantine, a Non-Competitive N-Methyl-d-Aspartate Receptor Antagonist
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7
作者:
Zhang, Yunpeng
;
Li, Shuping
;
Wang, Youxu
;
Deng, Gang
;
Cao, Ning
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
harmine
memantine
drug-drug interaction
pharmacokinetics
Alzheimer's disease
liquid chromatography-mass spectrometry
Subchronic toxicity and concomitant toxicokinetics of long-term oral administration of total alkaloid extracts from seeds of Peganum harmala Linn: A 28-day study in rats
期刊论文
Journal of ethnopharmacology, 2019, 页码: 111866
作者:
Wang Youxu[1]
;
Wang Hanxue[2]
;
Zhang Liuhong[3]
;
Zhang Yunpeng[4]
;
Sheng Yuchen[5]
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/04/22
Concomitant toxicokinetics
Harmaline
Harmine
Peganum harmala
Subchronic toxicity
Synergistic Effects and Mechanisms of Combined Treatment With Harmine Hydrochloride and Azoles for Resistant Candida albicans
期刊论文
FRONTIERS IN MICROBIOLOGY, 2019, 卷号: 10
作者:
Li, Xiuyun
;
Wu, Xuexin
;
Gao, Yan
;
Hao, Lina
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/11
harmine hydrochloride
azoles
resistant Candida albicans
Galleria
mellonella
synergistic mechanism
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Wang, Anhui
;
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/06/20
beta(2)-Adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
Naunyn-schmiedebergs archives of pharmacology, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
;
Qu, Lala
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/05/08
Beta(2)-adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:
Gu, Hongling
;
Li, Na
;
Dai, Jiangkun
;
Xi, Yaxi
;
Wang, Shijun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
bivalent -carbolines
antitumor
apoptosis
DNA-binding affinity
bcl-2
Analogous beta-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Wang, Chang-Hong
;
Li, Shu-Ping
;
Wang, Yu-Wen
;
Qi, Sheng-Lan
;
Zhang, Yun-Peng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
harmaline
harmine
scopolamine
systemic injections
memory deficits
cholinergic function
oxidative stress
inflammation
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