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复旦大学上海医学院 [11]
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Multi-omics fusion analysis models with machine learning predict survival of HER2-negative metastatic breast cancer: a multicenter prospective observational study
期刊论文
CHINESE MEDICAL JOURNAL, 2023, 卷号: 136, 期号: 7, 页码: 863-865
作者:
Wang, Jiani
;
Liu, Yuwei
;
Zhang, Renzhi
;
Liu, Zhenyu
;
Yi, Zongbi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2023/11/17
Integrated microbiome, metabolome, and proteome analysis identifies a novel interplay among commensal bacteria, metabolites and candidate targets in non-small cell lung cancer
期刊论文
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12
作者:
Qian, Xiang
;
Zhang, Hong-Yan
;
Li, Qing-Lin
;
Ma, Guan-Jun
;
Chen, Zhuo
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  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
all-trans-retinoic acid
gut microbiota
lung cancer
metabonomics
nervonic acid
proteomics
Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity
期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Shi, Xiaohan
;
Li, Yunguang
;
Yuan, Qiuyue
;
Tang, Shijie
;
Guo, Shiwei
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  |  
浏览/下载:32/0
  |  
提交时间:2022/06/21
Metabolic detection and systems analyses of pancreatic ductal adenocarcinoma through machine learning, lipidomics, and multi-omics
期刊论文
SCIENCE ADVANCES, 2021, 卷号: 7, 期号: 52, 页码: 13
作者:
Wang, Guangxi
;
Yao, Hantao
;
Gong, Yan
;
Lu, Zipeng
;
Pang, Ruifang
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  |  
浏览/下载:26/0
  |  
提交时间:2022/03/17
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
期刊论文
NATURE BIOTECHNOLOGY, 2021, 页码: 18
作者:
Sun, Duanchen
;
Guan, Xiangnan
;
Moran, Amy E.
;
Wu, Ling-Yun
;
Qian, David Z.
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  |  
浏览/下载:27/0
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提交时间:2022/04/02
Approximate distance correlation for selecting highly interrelated genes across datasets
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 11, 页码: 18
作者:
Shen, Qunlun
;
Zhang, Shihua
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  |  
浏览/下载:12/0
  |  
提交时间:2022/04/02
Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells
期刊论文
GENOMICS, 2021, 卷号: 113, 期号: 3, 页码: 1057-1069
作者:
Liu, Yuwei
;
Xue, Mengzhu
;
Cao, Danyan
;
Qin, Lihuai
;
Wang, Ying
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  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
Multi-omics
BET inhibitor responses
WNT pathway
Liver cancer
Precise therapy
A survey and systematic assessment of computational methods for drug response prediction
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 232-246
作者:
Chen, Jinyu
;
Zhang, Louxin
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  |  
浏览/下载:25/0
  |  
提交时间:2021/06/01
Drug response prediction
regression model
low rank matrix factorization based approach
Bayesian inference
deep learning
benchmark
DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5
作者:
Wang, Yongcui
;
Yang, Yingxi
;
Chen, Shilong
;
Wang, Jiguang
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  |  
浏览/下载:28/0
  |  
提交时间:2021/11/18
drug repurposing
multi-omics data sources
kernel-based data integration
machine learning
cancer precision medicine
DeepOmix: A scalable and interpretable multi-omics deep learning framework and application in cancer survival analysis
期刊论文
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 2719-2725
作者:
Zhao, Lianhe
;
Dong, Qiongye
;
Luo, Chunlong
;
Wu, Yang
;
Bu, Dechao
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/01
Multi-omics
Deep learning
Survival analysis
Prognosis prediction
Interpretable model
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