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上海药物研究所 [10]
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期刊论文 [16]
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
A versatile strategy to create an active tumor-targeted chemo-photothermal therapy nanoplatform: A case of an IR-780 derivative co-assembled with camptothecin prodrug
期刊论文
ACTA BIOMATERIALIA, 2019, 卷号: 84, 页码: 356-366
作者:
He, Wenxiu
;
Jiang, Yue
;
Li, Qian
;
Zhang, Di
;
Li, Zhonghao
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
Assembly
IR-780 derivative
Camptothecin prodrug
Redox-responsive
Chemo-photothermal therapy
Molecularly precise self-assembly of theranostic nanoprobes within a single-molecular framework for in vivo tracking of tumor-specific chemotherapy
期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 22, 页码: 4959-4969
作者:
Yan, Chenxu
;
Guo, Zhiqian
;
Shen, Yanyan
;
Chen, Yi
;
Tian, He
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  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Antitumor potential of a novel camptothecin derivative, ZBH-ZM-06
期刊论文
ONCOLOGY REPORTS, 2018, 卷号: 39, 期号: 2
作者:
Wu, Di
;
Zhao, Da-Wei
;
Li, Yong-Qi
;
Shi, Wei-Guo
;
Yin, Qi-Liang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
camptothecin derivative
antitumor
topoisomerase
proapoptosis
cell cycle
A versatile strategy to create an active tumor-targeted chemo-photothermal therapy nanoplatform: A case of an IR-780 derivative co-assembled with camptothecin prodrug
期刊论文
Acta Biomaterialia, 2018
作者:
He W.
;
Jiang Y.
;
Li Q.
;
Zhang D.
;
Li Z.
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Assembly
Camptothecin prodrug
Chemo-photothermal therapy
IR-780 derivative
Redox-responsive
Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation
期刊论文
Chemical communications, 2016, 卷号: 52, 期号: 98, 页码: 14145-14148
作者:
He, Dongxuan
;
Zhang, Wei
;
Deng, Hongzhang
;
Huo, Shuaidong
;
Wang, Yi-Feng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/04/23
Sequence selectivity of the cleavage sites induced by topoisomerase I inhibitors: a molecular dynamics study
期刊论文
NUCLEIC ACIDS RESEARCH, 2013
作者:
Siu, Fung-Ming
;
Pommier, Yves
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  |  
浏览/下载:9/0
  |  
提交时间:2015/08/28
New water-soluble camptothecin naphthenic amine alcohol derivative used for preparation of anti-tumor drugs.
专利
申请日期: 2013-01-01, 公开日期: 2013-05-22
作者:
SUN C JIANG B FAN Q SONG G QIAN Y G
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line
期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2012, 卷号: 360, 期号: 1-2, 页码: 329-337
作者:
Lu, Jin-Jian
;
Chen, Si-Meng
;
Ding, Jian
;
Meng, Ling-Hua
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Dihydroartemisinin
Resistant
Proteomics
Anti-tumor
HCT116
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 2, 页码: 261-270
作者:
Liu Zulong
;
Tian Wei
;
Wang Yong
;
Kuang Shan
;
Luo Xiaomin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/02/02
PHASE-I
ANTITUMOR-ACTIVITY
ANTICANCER AGENT
BINDING
APOPTOSIS
E7070
COLCHICINE
DISCOVERY
HMN-214
CAMPTOTHECIN
MPSP-001
sulfonamide
anticancer drug
microtubules
tubulin
mitotic spindle
drug resistance
drug synergism
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