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Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles
期刊论文
PHARMACEUTICAL RESEARCH, 2021, 页码: 22
作者:
Han, Sifei
;
Mei, Lianghe
;
Quach, Tim
;
Porter, Chris
;
Trevaskis, Natalie
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/11/04
conjugate
lipid
lymphatic
pharmacokinetics
prodrug
Conjugation of beta-Glucan with the Hydrazone and Disulfide Linkers Markedly Improves the Immunogenicity of Zika Virus E Protein
期刊论文
MOLECULAR PHARMACEUTICS, 2020, 卷号: 17, 期号: 6, 页码: 1933-1944
作者:
Qi, Jinming
;
Yin, Ying
;
Yu, Weili
;
Shen, Lijuan
;
Xu, Junjie
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/23
Zika virus
beta-glucan
E protein
adjuvant
hydrazine
disulfide
Temperature- and pH-dependent protein conformational changes investigated by terahertz dielectric spectroscopy
期刊论文
INFRARED PHYSICS & TECHNOLOGY, 2019, 卷号: 98, 页码: 260-265
作者:
Zang, Ziyi
;
Yan, Shihan
;
Hana, Xiaohui
;
Wei, Dongshan
;
Cui, Hong-Liang
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  |  
浏览/下载:71/0
  |  
提交时间:2019/12/03
Terahertz dielectric spectroscopy
Protein formulation
Protein unfolding
Temperature
pH
Effects of replacing soybean meal with cottonseed meal on growth, muscle amino acids, and hematology of juvenile common carp, Cyprinus carpio
期刊论文
AQUACULTURE INTERNATIONAL, 2019, 卷号: 27, 期号: 2
作者:
Su, Jianmei
;
Hou, Hongli
;
Wang, Chunhong
;
Luo, Yuliang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Plant protein sources
Feed formulation
Fillet characteristics
Cyprinids
Small molecules as inhibitors of PCSK9: Current status and future challenges
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.162, 页码: 212-233
作者:
Shengtao Xu
;
Shanshan Luo
;
Zheying Zhu
;
Jinyi Xu
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  |  
浏览/下载:11/0
  |  
提交时间:2019/12/13
PCSK9
protein
Inhibitor
Small-molecule
LDL-C
Hypercholesterolemia
Natural
products
Patent
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.
期刊论文
European journal of medicinal chemistry, 2019, 卷号: Vol.167, 页码: 485-498
作者:
Hong Yao
;
Feijie Xu
;
Guangyu Wang
;
Shaowen Xie
;
Wenlong Li
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/17
Anticancer
Deguelin
Heat
shock
protein
90
Structure
simplification
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors
期刊论文
European Journal of Medicinal Chemistry, 2019
作者:
Hong Yao
;
Feijie Xu
;
Guangyu Wang
;
Shaowen Xie
;
Wenlong Li
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/17
Heat
shock
protein
90
Deguelin
Structure
simplification
Anticancer
Bioequivalence of paclitaxel protein-bound particles in patients with breast cancer: determining total and unbound paclitaxel in plasma by rapid equilibrium dialysis and liquid chromatography-tandem mass spectrometry
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 1739-1749
作者:
Li, Junling
;
Li, Wei
;
Dai, Xiaojian
;
Zhong, Dafang
;
Ding, Yaping
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  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
nab-paclitaxel
bioequivalence
rapid equilibrium dialysis
unbound fraction
pharmacokinetics
Theory and practice of using solvent paramagnetic relaxation enhancement to characterize protein conformational dynamics
期刊论文
METHODS, 2018, 卷号: 148, 页码: 48-56
作者:
Gong, Zhou
;
Schwieters, Charles D.
;
Tang, Chun
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2018/11/05
Paramagnetic relaxation enhancement
Protein cosolute
Structure refinement
Molecular dynamics simulation
Monte Carlo algorithm
Xplor-NIH
FORMULATION OF THE PROTEIN SYNTHESIS RATE WITH SEQUENCE INFORMATION
期刊论文
MATHEMATICAL BIOSCIENCES AND ENGINEERING, 2018, 卷号: 15, 期号: 2, 页码: 507-522
作者:
Xia, Wenjun[1]
;
Lei, Jinzhi[2]
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/24
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