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CORC

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Isolation and characterization of three pairs of verrucosidin epimers from the marine sediment-derived fungus Penicillium cyclopium and configuration revision of penicyrone A and related analogues 期刊论文
MARINE LIFE SCIENCE & TECHNOLOGY, 2023, 页码: 9
作者:  Li, Yan-He;  Mandi, Attila;  Li, Hong-Lei;  Li, Xiao-Ming;  Li, Xin
收藏  |  浏览/下载：4/0  |  提交时间：2023/12/13
Cyclopiumolides A and B, unusual 13-membered macrolides from the deep sea-sourced fungus Penicillium cyclopium SD-413 with antiproliferative activities 期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:  Li, Yan-He;  Yang, Sui-Qun;  Li, Xiao-Ming;  Li, Xin;  Wang, Bin-Gui
收藏  |  浏览/下载：143/0  |  提交时间：2023/01/06
Antibacterial Alkaloids and Polyketide Derivatives from the Deep Sea-Derived Fungus Penicillium cyclopium SD-413 期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 11, 页码: 8
作者:  Li, Yan-He;  Li, Xiao-Ming;  Li, Xin;  Yang, Sui-Qun;  Shi, Xiao-Shan
收藏  |  浏览/下载：34/0  |  提交时间：2021/04/12
1)- Cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus Penicillium sclerotiorum endogenous with the Chinese mangrove Bruguiera gymnorrhiza 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 卷号: 16, 期号: 5, 页码: 542-548
作者:  Li, Jing;  Wang, Jun;  Jiang, Cheng-Shi;  Li, Gang;  Guo, Yue-Wei
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08
Verrucisidinol and verrucosidinol acetate, two pyrone-type polyketides isolated from a marine derived fungus, penicillium aurantiogriseum 期刊论文
Marine drugs, 2010, 卷号: 8, 期号: 11, 页码: 2744-2754
作者:  Yu, Ke;  Ren, Biao;  Wei, Junli;  Chen, Caixia;  Sun, Jinsheng
收藏  |  浏览/下载：22/0  |  提交时间：2019/05/10
Generation and characterization of a monoclonal antibody to penicillic acid from Penicillium cyclopium 期刊论文
AFRICAN JOURNAL OF BIOTECHNOLOGY, 2010, 卷号: 9, 期号: 21, 页码: 3026-3031
作者:  Lei, Hongyu;  He, Zuping;  Yuan, Hui*;  Wu, Jing;  Wen, Lixin
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/23
Penicillic acid is one of the main mycotoxins in moldy feedstuff and has toxic effect on livestock and poultry and probably humans due to food chain transmission. The objective of this study was to generate and characterize a monoclonal antibody to penicillic acid for the efficient detection of penicillic acid from Penicillium cyclopiumby immunological methods. To this end  penicillic acid was conjugated to bovine serum album (BSA) using the Mannich reaction and coupled with ovalbumin (OVA) by the method of 1-ethyl-3-(3-dimethyl-aminopropyl) carbodiimide hydrochloride (EDC) to generate artificial antigens penicillic acid-BSA and penicillic acid-OVA. A hybridoma cell line was obtained after fusion of mouse SP2/0 myeloma cells with spleen cells of BALB/c mice immunized with artificial antigen penicillic acid-BSA. A monoclonal antibody specific against penicillic acid was produced in vivo by this hybridoma cell line. Further analysis revealed that the monoclonal antibody to penicillic acid was of the IgG1 subtype  with a titer of 1: 2.05 × 105. The antibody to penicillic acid had no or less cross-reaction with mycotoxins  including aflatoxin B1  zearalenone  T-2 toxin and fumonisins and more importantly  it assumed an affinity of about 1.54 × 108 liters per mol. Our ability to produce a monoclonal antibody to penicillic acid provides necessary groundwork for the effective detection of penicillic acid in various tissues of animals and human  using the immunocytochemistry  Western blots and enzyme-linked immunosorbent assay (ELISA).  
Cloning of an alkaline lipase gene from Penicillium cyclopium and its expression in Escherichia coli 期刊论文
LIPIDS, 2003, 卷号: 38, 期号: 3
作者:  Wu, MC;  Qian, K;  Jiang, PH;  Min, TS;  Sun, CG
收藏  |  浏览/下载：0/0  |  提交时间：2019/12/27

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