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上海药物研究所 [18]
复旦大学上海医学院 [15]
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A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model
期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
作者:
Ya-Nan Geng
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
;
Feng Yan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/11/30
Gypenoside
Neuroinflammation
Blood brain barrier
High altitude cerebral edema
NF-κB signaling pathway
FPS-ZM1 inhibits LPS-induced microglial inflammation by suppressing JAK/STAT signaling pathway
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 100, 页码: 12
作者:
Wang, Lan
;
Zhao, Danfeng
;
Wang, Huan
;
Wang, Lele
;
Liu, Xiaohui
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/12/01
Inflammation
Microglia
LPS
RNA-seq
JAK
STAT signaling pathway
Sinunanolobatone A, an Anti-inflammatory Diterpenoid with Bicyclo[13.1.0]pentadecane Carbon Scaffold, and Related Casbanes from the Sanya Soft Coral Sinularia nanolobata
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7575-7579
作者:
Zeng, Zi-Rong
;
Li, Wang-Sheng
;
Nay, Bastien
;
Hu, Pei
;
Zhang, Hai-Yan
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  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
Sinusiaetone A, an Anti-inflammatory Norditerpenoid with a Bicyclo[11.3.0]hexadecane Nucleus from the Hainan Soft Coral Sinularia siaesensis
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5621-5625
作者:
Chen, Zi-Hui
;
Li, Wang-Sheng
;
Zhang, Zai-Yong
;
Luo, Hui
;
Wang, Jian-Rong
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  |  
浏览/下载:92/0
  |  
提交时间:2021/11/04
Ximaoglaucumins A-F, new cembranoids with anti-inflammatory activities from the South China Sea soft coral Sarcophyton glaucum
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 38, 页码: 10
作者:
Shen, Shou-Mao
;
Li, Wang-Sheng
;
Ding, Xun
;
Luo, Hui
;
Zhang, Hai-Yan
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  |  
浏览/下载:15/0
  |  
提交时间:2021/08/17
Soft coral
Sarcophyton glaucum
Cembranoids
Anti-inflammation
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:
Liu, Jian-Guo
;
Zhao, Danfeng
;
Gong, Qi
;
Bao, Fengxia
;
Chen, Wen-Wen
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase-3
bisindole-substituted aminopyrazoles
Alzheimer's disease
oxidative neurotoxicity
microglial inflammation
Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 9
作者:
Yang, Longhe
;
Ji, Chunyan
;
Li, Yitian
;
Hu, Fan
;
Zhang, Fang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/10
NAAA inhibitor
atractylodin
>
anti-inflammation
microglia
traditional Chinese medicine
Nitric oxide inhibitory iridoids as potential anti-inflammatory agents from Valeriana jatamansi
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9
作者:
Wang, Huimei
;
Song, Ziteng
;
Xing, Honghong
;
Shi, Zhaoyu
;
Wu, Peng
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
Iridoids
NO inhibitory activities
Valeriana jatamansi
Inflammation
Molecular docking
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
;
Tao, Lingxue
;
Wu, Lei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
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