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Revisiting the mechanism of enfuvirtide and designing an analog with improved fusion inhibitory activity by targeting triple sites in gp41 期刊论文
AIDS, 2019, 卷号: 33, 期号: 10
作者:  Xu, Wei;  Pu, Jing;  Su, Shan;  Hua, Chen;  Su, Xiaojie
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/05
Conserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors 期刊论文
2019, 卷号: 11, 期号: 7
作者:  Geng, Xiuzhu;  Liu, Zixuan;  Yu, Danwei;  Qin, Bo;  Zhu, Yuanmei
收藏  |  浏览/下载:14/0  |  提交时间:2020/01/03
Identification of a novel inhibitor against middle east respiratory syndrome coronavirus 期刊论文
Viruses-basel, 2017, 卷号: 9, 期号: 9, 页码: 12
作者:  Sun, Yaping;  Zhang, Huaidong;  Shi, Jian;  Zhang, Zhe;  Gong, Rui
收藏  |  浏览/下载:75/0  |  提交时间:2019/05/08
Small-molecule HIV-1 entry inhibitors targeting gp120 and gp41: a patent review (2010-2015) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2017, 卷号: 27, 期号: 6
作者:  Li, Wen;  Lu, Lu;  Li, Weihua;  Jiang, Shibo
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05
Site-specific Isopeptide Bridge Tethering of Chimeric gp41 N-terminal Heptad Repeat Helical Trimers for the Treatment of HIV-1 Infection 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Wang, Chao;  Li, Xue;  Yu, Fei;  Lu, Lu;  Jiang, Xifeng
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
An effective strategy for recapitulating N-terminal heptad repeat trimers in enveloped virus surface glycoproteins for therapeutic applications 期刊论文
CHEMICAL SCIENCE, 2016, 卷号: 7, 期号: 3
作者:  Lai, Wenqing;  Wang, Chao;  Yu, Fei;  Lu, Lu;  Wang, Qian
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/05
A novel bispecific peptide HIV-1 fusion inhibitor targeting the N-terminal heptad repeat and fusion peptide domains in gp41 期刊论文
AMINO ACIDS, 2016, 卷号: 48, 期号: 12
作者:  Jiang, Xifeng;  Jia, Qiyan;  Lu, Lu;  Yu, Fei;  Zheng, Jishen
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/13
Peptide fusion inhibitors targeting the HIV-1 gp41: a patent review (2009-2014) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2015, 卷号: 25, 期号: 2
作者:  Zhang, Dongmei;  Li, Wen;  Jiang, Shibo
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/19
Hydrophobic mutations in buried polar residues enhance HIV-1 gp41 N-terminal heptad repeat-C-terminal heptad repeat interactions and C-peptides' anti-HIV activity 期刊论文
AIDS, 2014, 卷号: 28, 期号: 9
作者:  Zheng, Baohua;  Wang, Kun;  Lu, Lu;  Yu, Fei;  Cheng, Maosheng
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus 期刊论文
JOURNAL OF VIROLOGY, 2013, 卷号: 87, 期号: 24, 页码: 13134-13140
作者:  Gao, Jing;  Lu, Guangwen;  Qi, Jianxun;  Li, Yan;  Wu, Ying
收藏  |  浏览/下载:19/0  |  提交时间:2016/06/23


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