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Treatment outcomes and prognosis of patients with primary and acquired BRAF-mutated non-small cell lung cancer: A multicenter retrospective study 期刊论文
GENES CHROMOSOMES & CANCER, 2022
作者:  Wang, Wenxian;  Gu, Xiaodong;  Si, Jinfei;  Pu, Xingxiang;  Wang, Liping
收藏  |  浏览/下载:31/0  |  提交时间:2022/05/16
Resistance mechanism of the oncogenic beta 3-alpha C deletion mutation in BRAF kinase to dabrafenib and vemurafenib revealed by molecular dynamics simulations and binding free energy calculations 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 2, 页码: 177-187
作者:  Niu, Yuzhen;  Zhang, Yan;  Yao, Xiaojun
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11
Dramatic efficacy of dabrafenib in Erdheim-Chester disease (ECD): a pediatric patient with multiple large intracranial ECD lesions hidden by refractory Langerhans cell histiocytosis 期刊论文
2019, 卷号: 23, 期号: 1, 页码: 48-53
作者:  Hao, Xiaolei;  Feng, Ruie;  Bi, Yalan;  Liu, Yuhan;  Li, Chunde
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
aberrantmodulationofribosomalproteins6phosphorylationconfersacquiredresistancetomapkpathwayinhibitorsinbrafmutantmelanoma 期刊论文
中国药理学报英文版, 2019, 卷号: 040, 期号: 002, 页码: 268
作者:  Mingzhao Gao;  Hongbin Wang;  Xiangling Chen;  Wenting Cao;  Li Fu
收藏  |  浏览/下载:6/0  |  提交时间:2020/07/01
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08
BRAF and EGFR inhibitors synergize to increase cytotoxic effects and decrease stem cell capacities in BRAF(V600E)-mutant colorectal cancer cells 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 4
作者:  Wu, Zhenhua;  Huang, Mingzhu;  Gong, Yiwei;  Lin, Chen;  Guo, Weijian
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 489, 期号: 1, 页码: 14-20
作者:  Wang, Hongbin;  Quan, Haitian;  Lou, Liguang
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:  Wang, Gui-min;  Wang, Xiang;  Zhu, Jian-ming;  Guo, Bin-bin;  Yang, Zhuo
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Potential Drug-drug Interaction between Dabrafenib and Insulin Secretagogue Repaglinide 期刊论文
LATIN AMERICAN JOURNAL OF PHARMACY, 2017, 卷号: 36, 期号: 8
作者:  Wang, Yong-Gang;  Wang, Shu-Dong;  Miao, Xiao;  Liu, Quan
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors 期刊论文
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068
作者:  Wang Guimin;  Wang Xiang;  Zhu Jianming;  Guo Binbin;  Yang Zhuo
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08


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