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科研机构
上海药物研究所 [22]
内容类型
期刊论文 [22]
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2021 [4]
2020 [2]
2019 [2]
2018 [4]
2016 [7]
2013 [1]
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Aristolochic acid I induces impairment in spermatogonial stem cell in rodents (vol 10, pg 436, 2021)
期刊论文
TOXICOLOGY RESEARCH, 2021, 卷号: 10, 期号: 4, 页码: 959-959
作者:
Liu, Yongzhen
;
He, Xiang
;
Wang, Yuli
;
Zhou, Houzu
;
Zhang, Yuan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/11/04
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes
期刊论文
LIFE SCIENCES, 2021, 卷号: 276, 页码: 13
作者:
Tai, Yusi
;
Pu, Mei
;
Yuan, Luyang
;
Guo, Huijie
;
Qiao, Junwen
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/08/17
Mitophagy
PINK1
miR-34a-5p
CDS
Non-seed region
Characteristic Malonyl Ginsenosides from the Leaves of Panax notoginseng as Potential Quality Markers for Adulteration Detection
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4849-4857
作者:
Yao, Chang-liang
;
Wang, Jing
;
Li, Zhen-wei
;
Qu, Hua
;
Pan, Hui-qin
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/08/17
adulteration
Panax notoginseng leaves
malonyl ginsenosides
quality markers
Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide +/ Sirtuin-1 pathway in mice
期刊论文
ASIAN JOURNAL OF SURGERY, 2021, 卷号: 44, 期号: 1, 页码: 213-220
作者:
Hua, Rong
;
Wang, Guan-Zhen
;
Shen, Qi-Wei
;
Yang, Ye-Ping
;
Wang, Meng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
NAD
NAFLD
NRK1
SIRT1
Sleeve gastrectomy
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:
Min, Wenjian
;
Hou, Zeng
;
Zhang, Fang
;
Xie, Shengnan
;
Yuan, Kai
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Histone methylation
Lysine methyltransferase
SET7
Small-molecule inhibitor
Virtual screening
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance
期刊论文
Science Advances, 2019, 卷号: 5, 期号: 2, 页码: eaau6328
作者:
Pan, Ruiyuan
;
Ma, Jun
;
Kong, Xiangxi
;
Wang, Xiaofeng
;
Li, Shuoshuo
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/04/02
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance
期刊论文
SCIENCE ADVANCES, 2019, 卷号: 5, 期号: 2, 页码: 15
作者:
Pan, Rui-Yuan
;
Ma, Jun
;
Kong, Xiang-Xi
;
Wang, Xiao-Feng
;
Li, Shuo-Shuo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
Solid-state characterization and solubility enhancement of apremilast drug-drug cocrystals
期刊论文
CRYSTENGCOMM, 2018, 卷号: 20, 期号: 39, 页码: 5945-5948
作者:
Wang, Feng-Yuan
;
Zhang, Qi
;
Zhang, Zaiyong
;
Gong, Xiaoyi
;
Wang, Jian-Rong
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2019/01/08
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:
Sun, Hui-jiao
;
Wang, Yu-hua
;
Yuan, Cong-min
;
Kong, Ling-hui
;
Xu, Xue-jun
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
7 beta-Methyl-nepenthone analogues
KOR ligands
Concept of hybridization
Opioid receptor binding and functional activities
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