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CORC

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Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1 期刊论文
ACS CHEMICAL BIOLOGY, 2018, 卷号: 13, 期号: 3, 页码: 772-781
作者:  Ye, Fei;  Kong, Xiangqian;  Zhang, Hao;  Liu, Yan;  Shao, Zhiyuan
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Discovery of novel DNA methyltransferase 3A inhibitors via structure-based virtual screening and biological assays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 2, 页码: 342-346
作者:  Shao, Zhiyuan;  Xu, Pan;  Xu, Wen;  Li, Linjuan;  Liu, Shien
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
thamnoliavermicularisextractimproveslearningabilityinappps1transgenicmicebyamelioratingbothaandtaupathologies 期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:  Li Cong;  Guo Xiaodan;  Lei Min;  Wu Jiayi;  Jin Jiazhen
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies 期刊论文
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:  Li Cong;  Guo Xiaodan;  Lei Min;  Wu Jiayi;  Jin Jiazhen
收藏  |  浏览/下载：5/0  |  提交时间：2020/12/24
Synthesis and decreasing A beta content evaluation of arctigenin-4-yl carbamate derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 2988-2991
作者:  Xu, Xingyu
收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08
A beta regulation-based multitarget strategy for drug discovery against Alzheimer's disease 期刊论文
REVIEWS IN THE NEUROSCIENCES, 2015, 卷号: 26, 期号: 1, 页码: 13-30
作者:  Guo, Xiaodan;  Jiang, Wei;  Li, Chenjing;  Zhu, Zhiyuan;  Shen, Xu
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08
Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both beta-Amyloid Production and Clearance 期刊论文
JOURNAL OF NEUROSCIENCE, 2013, 卷号: 33, 期号: 32, 页码: 13138-13149
作者:  Zhu, Zhiyuan;  Yan, Jianming;  Jiang, Wei;  Yao, Xin-gang;  Chen, Jing
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Design, synthesis and SAR study of hydroxychalcone inhibitors of human beta-secretase (BACE1) 期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2011, 卷号: 26, 期号: 5, 页码: 643-648
作者:  Ma, Lei;  Yang, Zhengyi;  Li, Chenjing;  Zhu, Zhiyuan;  Shen, Xu
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
2,2',4'-Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2010, 卷号: 114, 期号: 2, 页码: 374-385
作者:  Zhu, Zhiyuan;  Li, Chenjing;  Wang, Xu;  Yang, Zhengyi;  Chen, Jing
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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