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科研机构
上海药物研究所 [60]
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期刊论文 [59]
会议论文 [1]
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2021 [3]
2020 [5]
2019 [2]
2018 [7]
2017 [5]
2016 [6]
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The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis
期刊论文
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2021, 卷号: 11, 期号: 3, 页码: 697-724
作者:
Zhang, Linqiang
;
Zhang, Zhiguo
;
Li, Chengbin
;
Zhu, Tingting
;
Gao, Jing
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
NAFLD
S100A11
FOXO1
Autophagy
Lipid Metabolism
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:
Li, Zhiqiang
;
Li, Xinzhi
;
Su, Ming-Bo
;
Gao, Li-Xin
;
Zhou, Yu-Bo
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests (vol 14, 37, 2019)
期刊论文
CHINESE MEDICINE, 2020, 卷号: 15, 期号: 1, 页码: 1
作者:
Zhong, Ming
;
Tian, Xiaoting
;
Chen, Shuoji
;
Chen, Mingcang
;
Guo, Ziqiong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 293-302
作者:
Wang, Jin-tao
;
Zheng, Yue-ming
;
Chen, Yue-ting
;
Gu, Min
;
Gao, Zhao-bing
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Nav1
7 sodium channel
aryl sulfonamide
maprotiline
compound 10o
electrophysiology
acetic acid-induced visceral pain
analgesic activity
Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Xie, Zhu-qing
;
Tian, Xiao-ting
;
Zheng, Yue-ming
;
Zhan, Li
;
Chen, Xue-qin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
geissoschizine methyl ether
Uncaria rhynchophyll
antiepileptic drug
hippocampal neurons
action potential
nicotinic acetylcholine receptors
voltage-gated ion channels
mouse seizure model
discoveryofarylsulfonamideselectivenav17inhibitorswithahighlyhydrophobicethanoanthracenecore
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 293
作者:
Wang Jintao
;
Zheng Yueming
;
Chen Yueting
;
Gu Min
;
Gao Zhaobing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Nav1.7 sodium channel
aryl sulfonamide
maprotiline
compound 10o
electrophysiology
acetic acid-induced visceral pain
analgesic activity
Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests
期刊论文
CHINESE MEDICINE, 2019, 卷号: 14, 期号: 1, 页码: 11
作者:
Zhong, Ming
;
Tian, Xiaoting
;
Chen, Shuoji
;
Chen, Mingcang
;
Guo, Ziqiong
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Baihe-Zhimu decoction
Antidepressant
Timosaponin BII
Timosaponin BIII
Drug discovery
inhibitoryeffectsoflappaconitineontheneuronalisoformsofvoltagegatedsodiumchannels
期刊论文
中国药理学报英文版, 2019, 卷号: 040, 期号: 004, 页码: 451
作者:
Li Yanfen
;
Zheng Yueming
;
Yu Yong
;
Gan Yong
;
Gao Zhaobing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
voltage-gated
sodium
channel
1.7
analgesics
lappaconitine
tetracaine
bupivacaine
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