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科研机构
海洋研究所 [49]
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期刊论文 [46]
学位论文 [3]
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2024 [1]
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Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2024, 页码: 17
作者:
Li, Zhi
;
Wu, Ning
;
Wang, Jing
;
Yue, Yang
;
Geng, Lihua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/04/07
diabetic vascular complication
glycocalyx
insulin resistance
LMWF
NEU2
Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
;
Xing, Ronge
;
Yang, Haoyue
;
Liu, Song
;
Yu, Huahua
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
Co-activating the AMPK signaling axis by low molecular weight fucoidan LF2 and fucoxanthin improves the HFD-induced metabolic syndrome in mice
期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2022, 卷号: 94, 页码: 9
作者:
Deng, Zhenzhen
;
Wang, Jing
;
Wu, Ning
;
Geng, Lihua
;
Zhang, Quanbin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/17
Fucoxanthin
Fucoidan
Metabolic Syndrome
AMPK Signaling Axis
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13
作者:
Jiang, Bo
;
Luo, Jiao
;
Guo, Shuju
;
Wang, Lijun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/11
Type 2 diabetes mellitus
Protein tyrosine phosphatase 1B inhibitors
Thiazolidinedione
Insulin signaling
Anti-diabetic activities
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:
Zhang, Jiajia
;
Wu, Ning
;
Shi, Dayong
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/05/11
Signaling pathway
mammalian target of rapamycin
protein tyrosine phosphatase 1b
dipeptidase 4
cancer
diabetes
pharmacology
target compounds
Roles of Endovascular Calyx Related Enzymes in Endothelial Dysfunction and Diabetic Vascular Complications
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 13
作者:
Li, Zhi
;
Wu, Ning
;
Wang, Jing
;
Zhang, Quanbin
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2021/04/12
glycocalyx
vascular complications
diabetes
endothelial dysfunction
enzyme
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 163, 页码: 200-208
作者:
Luo, Jiao
;
Zhang, Renshuai
;
Wang, Xuehe
;
Hou, Zhanhui
;
Guo, Shuju
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/04/12
PTP1B
Bromophenol
Molecular docking
Surface plasmon resonance
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
The Risk of Gastrointestinal Hemorrhage in Low-Dose Aspirin Users with Diabetes Mellitus: Systematic Review and Meta-Analysis
期刊论文
GASTROENTEROLOGY RESEARCH AND PRACTICE, 2020, 卷号: 2020, 页码: 6
作者:
Wang, Yashuo
;
Wang, Wei
;
Wang, Bin
;
Wang, Yunyang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/09/29
Low molecular weight fucoidan alleviates diabetic nephropathy by binding fibronectin and inhibiting ECM-receptor interaction in human renal mesangial cells
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 304-314
作者:
Wang, Jing
;
Zhang, Quanbin
;
Li, Shuang
;
Chen, Zhihang
;
Tan, Jiaojiao
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/09/23
Fucoidan
ECM-receptor interaction
Fibronectin
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