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科研机构
数学与系统科学研究... [20]
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期刊论文 [20]
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2022 [3]
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专题:数学与系统科学研究院
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DATA-ADAPTIVE EFFICIENT ESTIMATION STRATEGIES FOR BIOMARKER STUDIES EMBEDDED IN RANDOMIZED TRIALS
期刊论文
ANNALS OF APPLIED STATISTICS, 2022, 卷号: 16, 期号: 4, 页码: 2250-2265
作者:
Zhang, Weiz
;
Zhang, Zhi wei
;
Troendle, James F.
;
Liu, Aiyi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/02/07
Augmentation
precision medicine
semiparametric theory
super learner
two-phase sampling
Biomarker interaction selection and disease detection based on multivariate gain ratio
期刊论文
BMC BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 16
作者:
Chu, Xiao
;
Jiang, Mao
;
Liu, Zhuo-Jun
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  |  
浏览/下载:7/0
  |  
提交时间:2023/02/07
Multivariate gain ratio
Biomarker interaction
Disease detection
hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 2, 页码: 16
作者:
Lu, Yong
;
Xue, Gang
;
Zheng, Ningbo
;
Han, Kun
;
Yang, Wenzhong
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  |  
浏览/下载:13/0
  |  
提交时间:2023/02/07
single-cell RNA sequencing (scRNA-seq)
single-cell mass cytometry (CyTOF)
Pareto optimization
projection-free single-cell modeling
response to immune checkpoint blockade
Group testing can improve the cost-efficiency of prospective-retrospective biomarker studies
期刊论文
BMC MEDICAL RESEARCH METHODOLOGY, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:
Zhang, Wei
;
Zhang, Zhiwei
;
Krushkal, Julia
;
Liu, Aiyi
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  |  
浏览/下载:80/0
  |  
提交时间:2021/04/26
Biomarker study design
Cost-efficiency
Group testing
Pooling
Two-phase sampling
Error-corrected estimation of a diagnostic accuracy index of a biomarker against a continuous gold standard
期刊论文
STATISTICS IN MEDICINE, 2020, 页码: 25
作者:
Wu, Mixia
;
Zhang, Xiaoyu
;
Zhang, Wei
;
Zhang, Xu
;
Liu, Aiyi
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  |  
浏览/下载:17/0
  |  
提交时间:2021/01/14
adaptive estimation
additive errors
asymptotic normality
biomarkers
diagnostic accuracy
measurement errors
reliability coefficient
A Branch Point on Differentiation Trajectory is the Bifurcating Event Revealed by Dynamical Network Biomarker Analysis of Single-Cell Data
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2020, 卷号: 17, 期号: 2, 页码: 366-375
作者:
Chen, Ziwei
;
Bai, Xiangqi
;
Ma, Liang
;
Wang, Xiawei
;
Liu, Xiuqin
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  |  
浏览/下载:23/0
  |  
提交时间:2020/05/24
Trajectory
Heuristic algorithms
Mice
Correlation
Reactive power
Pseudo temporal trajectory
branch point
DNB theory
reconstruction
single-cell data
bifurcation
dynamical system
Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 12, 页码: 20
作者:
Wang, Yongcui
;
Chen, Shilong
;
Chen, Luonan
;
Wang, Yong
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  |  
浏览/下载:54/0
  |  
提交时间:2020/05/24
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2019, 卷号: 20, 期号: 1, 页码: 89-101
作者:
Sun, Duanchen
;
Ren, Xianwen
;
Ari, Eszter
;
Korcsmaros, Tamas
;
Csermely, Peter
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  |  
浏览/下载:46/0
  |  
提交时间:2019/03/05
heterogeneous diseases
cancer biomarker
network-based
cooperative biomarker
gene expression
Network-Regularized Sparse Logistic Regression Models for Clinical Risk Prediction and Biomarker Discovery
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2018, 卷号: 15, 期号: 3, 页码: 944-953
作者:
Min, Wenwen
;
Liu, Juan
;
Zhang, Shihua
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2018/07/30
Sparse logistic regression
network-regularized penalty
survival risk prediction
feature selection
A novel computational model based on super-disease and miRNA for potential miRNA-disease association prediction
期刊论文
MOLECULAR BIOSYSTEMS, 2017, 卷号: 13, 期号: 6, 页码: 1202-1212
作者:
Chen, Xing
;
Jiang, Zhi-Chao
;
Xie, Di
;
Huang, De-Shuang
;
Zhao, Qi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2018/07/30
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