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CORC

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Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10
作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing
收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01
Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10
作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai
收藏  |  浏览/下载：49/0  |  提交时间：2020/07/01
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan
收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:  Lai Mengzhen;  Song Peiran;  Dou Dou;  Diao Yanyan;  Tong Linjiang
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening 期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:  
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair. 期刊论文
Journal of molecular cell biology, 2019
作者:  Xie Shuying;  Fu Wenbin;  Yu Guangju;  Hu Xueli;  Lai Kaa Seng
收藏  |  浏览/下载：38/0  |  提交时间：2019/12/05
HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. 期刊论文
Cell chemical biology, 2019, 卷号: 26, 页码: 331-+
作者:  Mo Xiulei;  Tang Cong;  Niu Qiankun;  Ma Tingxuan;  Du Yuhong
收藏  |  浏览/下载：33/0  |  提交时间：2019/11/19
Small molecules as inhibitors of PCSK9: Current status and future challenges 期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.162, 页码: 212-233
作者:  Shengtao Xu;  Shanshan Luo;  Zheying Zhu;  Jinyi Xu
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/13

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